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Peripheral Neuropathy
Since HSV is neurotropic, can genital HSV2 cause sensory peripheral neuropathy? If so, how often does this occur? Do most people usually make a full recovery from it? Is it like post-herpetic neuralgia that people with shingles sometimes experience?
I appreciate your input on this as there isn't much in the medical literature that I've seen discussing neurological symptoms from HSV.
One additional question, what are the odds that a negative type-specific Herpes Select test at 16 weeks post-exposure would be a false negative, in terms of percentages?
I appreciate your input on this as there isn't much in the medical literature that I've seen discussing neurological symptoms from HSV.
One additional question, what are the odds that a negative type-specific Herpes Select test at 16 weeks post-exposure would be a false negative, in terms of percentages?
A related discussion, herpes and neuropathy was started.
Badluck7- Let me know how your tests go. I'm in the same boat you are in. Thanks.
MEDICAL PROFESSIONAL
To my knowledge, prior HSV-1 infection has no influence on time to seroconversion for HSV-2. If anything, I would expect it might be faster than otherwise, but I don't know this.
HHH, MD
HHH, MD
As an addition to the Herpes Select test question - would being positive for HSV-1 orally lengthen the time to seroconversion for HSV-2? And would beginning anti-virals a few weeks post-exposure also lenghten the time to HSV-2 seroconversion? Thanks.
MEDICAL PROFESSIONAL
To my knowledge, neuropathy due to HSV-2 has not been proved to occur with any frequency in the absence of overt genital herpes (although it wouldn't surprise me if there are a few individual case reports). On the other hand, nobody has done the right kind of research to work this out--i.e., a series of patients with otherwise unexplained peripheral neuropathy and controls without neuropathy, tested for HSV-2 antibody. If that showed suggestive results, confirmation might come in a placebo controlled treatment study to see if antiherpetic therapy helps.
Bottom line: I wouldn't be at all surprised if HSV-2 in fact explains some cases of overt sacral nerve neuropathy, unexplained period back and leg pains, etc. But in the absence of data, ther is just no way to know.
HerpeSelect HSV-2 is postitive within 16 weeks in at least 90%, probably 95% of infected persons. But a few false-negatives continue, perhaps indefinitely.
Regards-- HHH, MD
Bottom line: I wouldn't be at all surprised if HSV-2 in fact explains some cases of overt sacral nerve neuropathy, unexplained period back and leg pains, etc. But in the absence of data, ther is just no way to know.
HerpeSelect HSV-2 is postitive within 16 weeks in at least 90%, probably 95% of infected persons. But a few false-negatives continue, perhaps indefinitely.
Regards-- HHH, MD
You are reading content posted in the STDs Forum
Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.
