How accurate is the Rapid Plasma Reagin, Nontreponemal test, RPR, Syphilis serology done at 6 and a half weeks in detecting syphilis with or without outward signs of infection? Is 6 and a half weeks long enough time to detect the bacteria. Is 10 days of doxycycline 200 mg a day adequate to kill the bacteria?
thank you
Dr Hook
I never doubted any information you gave here and have appreciated how you have helped educate so many of us who were raise uninformed about stds. I am new to the dating scene after losing my wife of thirty five years last year to cancer. I have taken to heart all you have said but have been somewhat fascinated by the bacteria that cause syphilis. There is so much misinformation online about the transmission of stds that many are misinformed about transmission and course of treatment. You offer many here the ability to separate fact from fiction, and old wives tales many of us were told as children. I must admit I have tried to research how doxycline stops the reproduction of the bacteria by inhibiting certain proteins, unfortunately I am an engineer and always trying to understand things, thank you for you education and your patience.
You are having trouble letting go of the idea that you have syphilis and it appears that my answers only fuel your concerns. This will be the last answer.
The RPR a 6.5 weeks is highly accurate for syphilis, once again indicating that you do not have syphilis.
Doxycycline for syphilis treatment is recommended at a dose of 100mg twice daily for 14 days.
End of discussion. EWH
Yes, primary syphilis lesions (called chancres) appear as open sores. EWH
Thank you for your answer Doctor I was wondering if you could explain what the first stage syphilis lesion looks like. Is it always an open sore that oozes the bacteria, from what I have read and seen in pictures it often looks like a crater? Can it manifest as just a hard sore red in color with no crater or oozing
Thank you for you forums and quick responses, your service is invaluable to many of us who read the information regularly
Welcome to the Forum. The answer is, that yes, at least IN THEORY, syphilis can be transmitted without sexual intercourse. Syphilis is transmitted when there is direct contact between the sore on an infected person and an uninfected person. It is thought that the friction of sex helps to introduce the bacteria to cause infection.
Having answered your "is it possible" question, let me now elaborate to tell you why the lesion you saw was almost certainly NOT syphilis. Syphilis is not passed through clothing or from a lesion to another person on someone's hand. Furthermore, it is a fragile organism which does not live long enough to be transmitted through the contact you describe. You state that the area where your sore appeared was covered throughout you interaction with this woman. That assures you that the lesion that you describe was not syphilis. The lesion that you describe, both by location and your description was likely a folliculitis lesion which did not progress to form pimples or, as per your suggestion, might have been poison oak or some other skin condition.
I am confident that you do not have syphilis and see no need for testing. If my reassurance is insufficient however, I suggest you go to a local STD clinic and get a syphilis blood test. If the lesion you describe was syphilis, I can assure you, your blood test would be positive at this time.
Hope these comments are helpful to you. EWH