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Question about the Risk and TPPA

Hai,doctor

I had sex with a girl one week ago(french kiss, with condom).Yestoday, we went to hospital and had serologic tests,the result make me warried. Follows are the resluts of us.

(1) She: Trust positive (1:8); Tppa positive(1:320)
(2) Me : Trust negative; Tppa negative

The doctor advised that I should be  treated with 2.4 million units of Benzathin Penicillin once a week and maintain for 4 weeks. I accepted the advice and have the frist injection yestoday.

I know syphilis  is easy to cure in its early stages. But I am warry abot the resluts of serologic tests. Because I will  leave school in several month. In my country(Chinese mainland), the person who have syphilis is quite difficult to find a job, and employers often ask you to have a TPPA test. So my questions is following:

(1) Do i have high risk be infected syphilics?

(2) If i am treated in very early stage(less than 7days after sex behavior, and Trust negative; Tppa negative), can I prevent the TPPA turn positive? Or will TP-PA  finally turn positive once infected?

(3) When i have a test can exclude the possibility of infection of syphilis,if i had used antibiotic

(4) Will the using of antibiotic extend the  period which serologic test can't show its reliable result?

Thanks for your answer!
8 Responses
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300980 tn?1194929400
MEDICAL PROFESSIONAL
Your TPPA would only be positive itf you caught disease.  Again, no reason for concern.   EWH
Helpful - 1
300980 tn?1194929400
MEDICAL PROFESSIONAL
Your questions are rather difficult for me to follow.  Your treatment will prevent you from getting syphilis.  I urge you not to worry.  EWH
Helpful - 1
300980 tn?1194929400
MEDICAL PROFESSIONAL
Welcome to our Forum. As I understand it and interpret your test results, your partner has syphilis and you do not have evidence of infection.  The incubation time in which it takes syphilis to develop is, on average, 21 days.  A single treatment  with benzathine penicillin in the dose you received is completely effective in preventing development of syphilis.  The CDC's recommendation for persons in your situation is a single injection of penicillin with no need for further treatment or follow-up.

In answer to your questions:
1.  No, the preventative treatment is completely effective.
2.  Yes, the treatment should prevent your TPPA from becoming positive.
3.  Repeat testing will be negative.  If you had contracted syphilis, a blood test in 6-12  weeks would be positive.
4.  No, because the antibiotic will PREVENT the infection.

I hope this helps,  Now that you have been treated, you have nothing to worry about.  EWH
Helpful - 1
300980 tn?1194929400
MEDICAL PROFESSIONAL
Thank you. Take care.  EWH
Helpful - 0
Avatar universal
dear sir:
       I have read your paper "Azithromycin Compared with Penicillin G Benzathinefor
Treatment of Incubating Syphilis" and understanded what you said was base on strict experiment.
  
      I will show my respect to your professional spirit.

      
Helpful - 0
Avatar universal
I so appreciate your help and consolation

I undersand warry is useless.I will follow up in the following several month and consult you next time if have any problem.

Thanks again...
Helpful - 0
Avatar universal
thank you, thank you very much...

in fact, i am not worry about the disease but the TPPA...

thanks and god bless
Helpful - 0
Avatar universal
Thanks for your  explanation that make me relax a lot. But I' am still confused about something.

First: What dose this sentence mean" If you had contracted syphilis, a blood test in 6-12  weeks would be positive. "
Dose it mean: if you contracted syphilis, no matter how early you star to have a treatment, the blood teat will turn positive finally? Did I contract?

Second: some reports said that some infected people have reduce rpr, even turn rpr negative through a regular treatment following the CDC's recommendation strictly, and doctor also thought the disease has been cured. But after 2 or 3 year, the disease relapse.

What cause this phenomenon happen (Will a tiny amount of bacterium hide in human body no matter how much antibiotic he receive? Or the patient not receive enght antibiotic?), and will this phenomenon  fall upon me?

I am so sorry for my chatte. Thank you!
Helpful - 0

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