Yes,infectious mononucleosis can be associated with swelling of the joint as well as joint pain.It is because infectious mononucleosis which is often caused by Epstein barr virus can cause infectious arthritis. Infectious arthritis may be caused by bacteria, viruses, or fungi.This type of arthritis is usually sudden in onset, symmetric and polyarticular in distribution (fingers, knees, wrists), brief in duration (less than a month), and without residua.So the swelling produced by these viruses lasts no more than one to two weeks.No antibiotics are needed for viral infectious arthritis and usually it is self limiting.
Hope this helps.Take care and pls do keep me posted if you have any additional doubts.
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