Swollen lymphnodes and enlarged spleen

[Cinbad]

I have a 4 year old neice who has swollen lymphnodes in several areas of her body that was recently discovered.  she has had an ultrasound and blood work, and was told her spleen is enlarged as well.  what could this be?

[BhumikaMD]

Hi,

By mono I guess you refer to Infectious mononucleosis, more commonly known as glandular fever in other English-speaking countries. It occurs most commonly in adolescents and young adults, where it is characterized by fever, sore throat, muscle soreness, and fatigue. Infectious mononucleosis typically produces a mild illness in small children, and is often asymptomatic. Mononucleosis is predominantly caused by the Epstein-Barr virus (EBV), which infects B cells (B-lymphocytes), producing a reactive lymphocytosis predominantly consisting of atypical lymphocytes, a specific type of T-cell that gives the disease its name.

A diagnosis of Mono can be established through examination and tests. Though, the EBV virus may remain dormant for some time and resurface at a later date. Please confirm this from a doctor though it is clear that the disease may be resurfacing of a previous infection.

You can get more information at : http://en.wikipedia.org/wiki/Infectious_mononucleosis

Best regards

[borninquisitive]

I second the mono guess. Also, beings that she has an enlarged spleen, you want to keep her from contact sports and rough housing.

[glad2bamom]

Mononucleosis can cause these exact symptoms.  Fatigue and sometimes a sore throat can be present with this as well.  Generally, a pediatrician's office can test for this via a blood test.  There is nothing they can do, as it is viral, but they will limit her activity level.  Also, mono is contagious.