I am 76 year old man diagnosed with stage 4 prostate cancer. PSA was 14. CT showed mass in bladder which was prostate cancer which had spread. Gleason was 8. Bone scan showed small focal met in back, rib and pelvis. TURP removed mass in bladder. Started with Firmagon and then Eligard every 4 months. First PSA after starting was 2.8. 4 months later ( 2 weeks after shot) it was 2.6. Last PSA 2 weeks before next 4 months shot it was up to 4. My primary Dr said its normal for some for PSA to be lower right after shot and higher right before next shot and that everyone is different. To say the least I am concerned and wondered if anyone else has had this same issue and what professionals on here might add.