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dropping the Effexor/Lexapro weight gain

Can anyone give me an idea of how long it usually takes for your metabolism to recalibrate after stopping Effexor and/or Lexapro?  I've gained significant weight while on these drugs (despite an intense exercise program and careful diet).  My nutritionist and MD told me that the drugs likely altered my metabolism, but no one can tell me how long it will take to correct that.  Most frustrating, I've noticed that since I stopped taking both, my weight gain has accelerated.  Any ideas as to how long I need to endure this or ideas for correcting my metabolism?  Thanks.
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Avatar universal
happened upon this forum by chance. I was started on Lexapro by my doctor 8 months ago for depression and anxiety. initially 10mgs daily then increased to 20mgs. I have noticed that I have gained weight even though I adhere to a strict diet and try to exercise as much as I can. having adult hip dysplasia curtails exercise somewhat. the weight that I've put on seems to be around my stomach area, I've gone from 30inch to 33 inch waist in the matter of a few months which is not good for my self esteem. being treated for depression then ending up being depressed about weight gain doesn't seem to be conducive to well being
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could you please explain the running regimn you were doing like how much a day and outside or treadmill  etc
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OMG you are soo right!  I had not realized it until I read your post, but all my life, when I am sad or stressed I have LOST my appitite and weight.  But NOW, when I am stressed I want carbs, carbs and more carbs.

Like most, Lexapro has been a god send for me...I was put on by a cardiologist to control my neurocardiogenic syncope...and it does.  However, I just keep piling on the pounds.  Now, my general doc says either take the weight off or go on a med for my cholesterol which is creeping up along with my weight...

So, last week I cut my 10 mg pills in half and will take this for 2 weeks.  Then I will alternate 1/2 and 1/4 of a pill for 2 weeks.  Then I will take 1/4 a pill a day for a week and stop altogether.  I have started taking a multi vitamin every day as someone had mentioned certain vitamins help.

I may change the length of time between reduction of dose depending on my side effects...I drive all day long so I simply can not tollerate being dizzy behind the wheel.  Hopefully this will not be a problem.  I have to have surgery and will be out of work for 2 weeks and am hoping that going off will coincide with this so that if I DO experience side effects I will not be driving at the time.
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How funny..that you call it "fake" weight...I do too.... I have been on Lexopro and Prozac in the past and after I got off of Prozac...I gained 30 lbs in less than 2 months.   Most recent I gained 20 lbs in less than 3 weeks.   HOW FRUSTRATING!

It is all in my middle area...and i look like I am 7 months pregnant.   grrrr.  
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I have taken Lexapro in two rounds. The first time I was on for 1 year and even after tappering off I had shocks, dizziness, and sweats terribly for 7 days after stopping the medicine. I had went from 145 to 175. After I quit taking lexapro I lost about 20 lbs in 2 months with diet and exercise only. Well now I was put on Lexapro again back last Dec 2010. I was 155 and now I am 196. I eat healthy and exercise with a trainier. With about a 5 lb loss. And Yes I am bloated where I feel I cannot breath. My face is a moon shape double chin, I never had this even when I was pregnate with both of my girls and topped the scale at 200 lbs on delivery. I believe weight loss is possible but only if you get off Lexapro.
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Avatar universal
i have been on lexapro for 6months and have put on 7kgs.. i started taking half of my 10mg today and only just came across this site tonight... i knew these tablets were the reason i was gaining weight. i noticed straight away i was eating more... coming from a person who would snack through out the day and only having a proper meal at dinner.. soon as i started on lexapro i was having the 3 meals a day and snacks.. hungry all the time which is not like me. the first 3 months i felt so happy then i started being over tired always, lazy and not wanting to have a social life at all... that is not me.. even when i was extremly low before lexapro my social life was something that made me happy.. being alone was what made me sad... now id rather be home alone and down then being around friends,family etc.,. i am becoming very moody and my weight is just making me more sad.. time to get off this thing!! i think lexapro is only good for people to help them overcome stress and tough times and once u feel happy again thats when u should get off,
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Arlington, VA
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