AI related?

[Mom2four85]

I've been going to dr's trying to find out what's wrong and went to a rheumy who did a ton of  tests.  

Today he gave me the results and said he really expected me to have reactive arthritis or something else like my primary thought with RA or OA; nothing specific was found just results and said he feels it's AI but has no clue what is going on.  He said he had to name it something and put a code on it so for now it's autoimmune inflammatory arthritis and sent me for an eye exam and prescribed Plaquenil to see if it will help.

Do any of these test results mean anything to anyone? I've had a ton of symptoms (noted in my journals) for at least 10 years.

C-Reactive Protein - 7.6 [0.0-4.9]
Beta Globulin 1.3 [0.6-1.3]  
Complement CH50 - >61 [22-60]
C3 -196 [90-180]
C4 - 31 [9-36]

I'm going to an Endocrinologist in a couple of weeks for thyroid problems.

[ewford]

An infectious disease doctor has very little to no knowlege of these infections.  There are too many symptoms for them to believe you and your labcorp Lyme tests were negative, so he won't even go there.  Doctors are told almost next to nothing about infectious mycoplasmas because their teachers don't know/divulge info.  Researchers on the cellular level are finding out alot of unexplained illnesses are caused by Lyme/Mycoplasmas/coinfection and fungal infections. like I said, go to Jemsek Specialty  Clinic website in DC and READ.  I think you will find your answers that have been denied to you for so long.  If you get proper testing and get treatment, please pass the word around.


  Dr Garth Nicolson is a HUGE asset and his information cannot be overlooked.  He was head of the Anderson Cancer Research Facility for the US Gov't and has done extensive research on mycoplasmas.  He has written over 3 world renown Citation papers, and over 300 peer reveiwed and accepted papers.

[Mom2four85]

thanks for the info; yes Lyme was negative but i've found negative isn't always negative =) in some cases

I'm wondering if I should see an infectious disease dr? I'm not sure the next step to take or what they even treat but someone recommended I see one.

I had Group B Streptococcus in 1997 that turned septic and was almost fatal; during my pregnancies in 2000 and 2002 I did test positive again, but my GYN did another test in Feb 2011 and said it was negative.

Then in March 2011 my primary took urine samples after I told her i've still had problems with very frequent urination (40-60 times daily) which showed Epithelial cells 10-20, WBC 2++ (20-40); Tr Ketones and Bacteria – Moderate; but there was no infection in the followup cultures they ran; but it did show I had 30 mg/dL protein.  I then had a 24 hr urinalysis that was within normal limits.

I will definitely read and find a doctor who knows something about all of this; I'm tired of being sick all the time.

[ewford]

Even down to the Endometriosis.  Most women I have interviewed have had a hysterectomy, but Endo is also very prevalent.

You need to search for www.ilads.com (International Lymes And Associated Disease Society) and have them find a Lyme literate doctor near you.  This can be cured as it is a chronic intracellular bacterial infection.  If you can also read  CURE UNKNOWN which is an excellent resourse.  You will understand why no standard medical doctor can figure this out partly because the tests designed for Lymes are wildly innacurate.  They were designed on a very narrow set of criteria and for monitoring purposes only.  But doctors don't understand that.  They see the "neg" result and say you don't have Lymes.  This bacteria and coinfections totally dissables your immune system and the immune system cannot activate an aggressive response.  the bacteria then gets into every body tissue and body fluid, corkscrewing through blood vessles into tissue.

  Also research www.immed.org and look under Autoimmune Illnesses.  Dr Garth Nicolson is an expert and his research is on the forefront of cellular level.

[Mom2four85]

opps that should be >61

[Mom2four85]

Thanks for the response and explanation; he told me I had all over body inflammation but didn't say what each test was.  A neurologist I was seeing in 2010 said she thought I had Lupus did an ANA which was negative and negative again now.

I just had full panels for everything including AI because I've been sick with a long grocery list of symptoms for about 10 years but my primary wouldn't send me to a Rheumatologist; so I had to wait for new insurance to kick in this year to go on my own.

Everything came back within normal range except those I've listed.  I'm confused though why my CH50 just says >60? not a specific number just over the 60 limit is that how it's normally done? I'll ask the dr but don't go back to see him for 4 months unless I have a new symptom or problems with plaquenil.

I'm not sure what to do next; he knows the inflammation is there and going to treat the symptom but has no clue what's causing it.  I do go to an Endocrinologist in a couple of weeks so maybe he'll do some tests also...I'm stumped and feel miserble.

[sjkly]

C-Reactive Protien measures inflamation-you have some but not all that much.
Complement CH50 measures specific autoimmune activity and you have some but not much more than a "healthy" person.
Has anyone done, ANA, Anti-DNA, RF or other more specific autoimmune tests?

By the way the other tests, Your results are low positives-that doesn't neccessarily correlate with how you would feel.  You can have AI diseases and be really ill without any positve test results.