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Constant Joint Pain

Hi,
I have most of the symptoms above (achiness, flu like symptoms, joint and muscle pains, swollen feet, blurred vision, feeling very cold always, very painful periods, itchiness, trouble concentrating, rash, irritability, fibromyalgia, gained 40lbs) but I have a temperature of about 99.8. Blood tests always come back normal, exept it shows slight inflammation. Doctors are not sure of what I have. Think it might be rheumatoid arthritis or sarcoidosis although my blood tests are never conclusive. Please do you have any suggestions? I have had these issues for years and they are getting worse. I am on methotrexate now and still have a lot of pain and a hard time walking. I am 33. Could it be my thyroid (although blood tests are normal)? Please any tips, suggestions, referrals are welcome. Thank you much

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Avatar universal
Have your doctors run a serum IgG subclass breakdown test. The resulting four profile points are very helpful in identifying the class of autoimmune action - if there is one.
Helpful - 0
1530171 tn?1448129593
Hi Akua.

Can you send me your thyroid test results with lab reference values?
Interpretation can vary widely and what may be considered within normal range, may not be so.

As far as infectious disease specialists, beware that they are governed
by the Infectious Disease Society of America, which does not recognize the chronic nature of some of the Pathogenic infectious conditions I mentioned earlier. ??????

An LLMD (Lyme Literate Medical Doctor) maybe able to help you with
ruling out a Pathogenic Infection, as they also deal with all the Lyme coinfections.

Another thing you may want to rule out is MTHFR gene mutations which
maybe a factor in your etiology.
Let me know if you want to pursue this and I can give you some details.
It's not as complicated as many people may think.

Best wishes from Greece (where I am staying till September)
Niko
Helpful - 0
Avatar universal
Hi Niko,
I contacted

Dr. Nicolson and some doctors from the website you recommended but haven't heard back from them yet. I also comtacted the infectious diseases department and made an appointment.

In the meantime, the  free T3, free T4 AND reverse T3 results came back normal. Is there any thing else you might recommend?

Thank you.

Helpful - 0
1530171 tn?1448129593

Hi Akua.
I'll send you this information in a message.
Just look in your inbox for it.
Helpful - 0
Avatar universal
Thank you so much, Niko! Do you know anyone in the Boston or surrounding areas who could help diagnose me and/or perform these tests on me?

Best,
Akua
Helpful - 0
1530171 tn?1448129593
You may have seronegative arthritis with an underlying low infectious condition, which when inactive does not show in blood tests.
It is common such infectious conditions in arthritic conditions  are localized mainly in tissue and specifically in synovial fluid within the joints evading the immune system and detection from blood tests as well.

It is possible you also have low thyroid function, in which case it is type 2,
thyroid resistance which again does not show in standard thyroid tests.

You must ask for free T3, free T4 AND reverse T3.

Normally basal temperature in low thyroid function would be low, but because of underlying infectious conditions the temperature rises.

It is possible also that the suspected infectious condition is of the pathogenic mycoplasma species and/or its coinfections, like babesia, bartonella, ehrlichia and others.
For more details on this please do a search here under Dr Garth Nicolson,
a part-time medhelp contributor and the world's leading expert in this fileld.

I hope this helps.
Niko
Helpful - 0
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