So I will be very honest as this is a topic hard for me to talk about. I have suffered from depression since i remember. As a teenager i used to cut my arms with razors and many times put my dads gun to my head. At 18 I went off to college and things got better and happier. Then marriage, children and a full time job happened and stress took over. I have been put on many antidepressants like prozac, wellbutrin, effexor, fetzima etc. A migraine last year made me have seizures for the first time in my life and a neurologist put me on topomax to control the migraines. It made me feel funny so i never took it and decided to live with the migraines. This August my father passed away and i went in a deep depression. Psychiatrist put me on Fetzima 40 mg wich i was already taking and Seroquel 50 mg. Been on it for about a week and feeling better. Then my neurologist tells me i need to get off Topomax and get on Lamictal. When the depression hit bad the headaches got bad again so i started taking the topomax and side effects vanished. I loved topomax and now they tell me to get rid of it. So today i took the first Lamictal 25 mg and will take another lamictal 25 mg at night with seroquel but i still want to keep taking the topomax and want to know if anyone had done this combo.