Just like all meds for mental illness, you shouldn't expect a change for several weeks. If you are calm on day 2, then it is you, not the drug. Also, Depakote has to reach an effective range in your blood stream which means you will have blood tests to see if you are in the therapeutic range.
Just took on day 2, iam very calm all day so far. Day1 didnt feel nothing. Iam not bi-polar.... iam way more adhd, so far this drug has help me with focus but kinda out of it. Feel like my metabolism has gone way down. Not sure if this drug is for me yet, Thinking concerta or adderall. But will give this drug a chance week or so at best, next doc appt is Oct 4th 2011.