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874521 tn?1424116797

"OVER"TIREDNESS

I'd appreciate some quick opinions again please.
My son is on zyprexa 10mg and depokate 1000mg both at p.m.
this is 4 weeks now....these last 2 weeks he has just stabilizes into an EXTREMELY DEPRESSED mode.
With also EXTREME tiredness.he lays down rt after his supper (abt 7) and falls asleep and can sleep for well so far this a.m. its been 16 hrs.
when he does wake up he is still tired, which I know is also a sign of depression, but has never been his pattern.
Therefore I suspect the medications. He cannot change the 10 mg of zyprexa until his pdoc apt on monday....HOwever he could lower the depokate on his own as 1000 mg is a high dose...does this med. also cause 'severe' tiredness?
4 Responses
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574118 tn?1305135284
Hi Opus88

I hundred per cent agree with IL. I hate zyprexa, although an atypical AP and very strong MS but very sedating. I read they give it as a strong mood stabilizer too but it will make him tired. Depakote (valporate) is good for mania rather than depression. The meds given will not elevate him up on the contrary will make him slip down, as a matter of fact i would be astonished if it didn't.

BP is a physical mood swings. The witty pdoc tries to give something that lessens the fluctuations in the mood which every "normal" people have incidentally but with a smaller amplitude. So it's futile to give something to take off the mania neither to lessen the depression alone. Meds vary of course according to the type of BP so they focus on lithium say when mania or hypomania is more pronounced while for depression (the difficult part) they either give lamictal or an AD to help. So your meds I guess aren't suitable. Besides this zyprexa of Eli lilly has been on the market for a while and known to be strong. pdocs use it as a mood stabilizer sometimes especially when there are psychosis. Why i don't know !    

I remember to have forwarded my theory and i shouldn't stress upon much for i may confuse others since i am not a pdoc just an amateur . But the best combo is one AC + one AP. Now which. Either lamictal+seroquel, or to combine 2 meds that one elevate and one suppress. If pdoc prefers to use AP's only then i recommend abilify+seroquel both are newer drugs than olanzapine (zyprexa) abilify is activating very good for depression like lamictal not sedating the only drawback is a bit of anxiety which seroquel can take care of, also the latter is a strong antimanic but also will NOT worsen depression like the rest of the typical AP's say. I bet one doesn't combine lamictal+abilify because both work upwards only although lamictal is an MS. Seroquel is my salvation drug (i am not a sales agent of the company of course) but it saved my life and I am BP1 the worst of them all. the company sells this drug like no other company had profited from any other drug. I read it's the 4th drug sold worldwide and made some 40 billion out of it, the patent will end in 2011 so another companies will take over but i assume the generic type only.

You have in my view to discuss his drugs with his pdoc. The problem when a pdoc tries somethimg on some patients they keep going with it on others this how it goes. because he can't open the brain of the patient to see which drug is convenient, so the direct approach is to keep trying and truying and the poor guy gets fired from his job or lose his bachelor degree like i did. Until i took over myself, i tried lamictal (2mg only as i have something called idysicratic only bear small doses). one advised lithium. i refused. one advised depakote i refused too (much weight gain and losing hair, it's very classical too and sure is good for mania only, because i also have a theory here: BP are dangerous criminals when in mania (this is how the society looked in the past at them usually they put them in aylum and hospitals) so they better be must be isolated in order not to hurt others. Hence the 3 classical British mentioned in their books meds for this (lithium,depakote, tegretol) must be to knock on the patient's head as simple as that. Later the society felt pity and tried to understand the situation so they intervened with MS to lessen these fluctuations, until they decided for some which makes the patient void of depression (abilify, lamictal) these are historical reflections that i did to realise how things develop, and i bet this is how things went in the past. So the classical three's must be good mainly for mania and although they say lithium is good for depression i bet this is wrong and we have monkeryc as a typical counterexample who took effexor for 6 months, why should he if lithioum is supposed to help him also.

sorry for this long letter, in short try another pdoc. I wonder if they teach in the medical schools logic and reasoning or just meds and drugs
good luck
ezz
Helpful - 0
Avatar universal
I know for a fact that the zyprexa causes drowsiness. I have been on 10mg for over a year and it makes me sleep well through the night and into the morning. I'm not sure about the other drug, but the one thing I am sure of is don't let him just get off the zyprexa "cold turkey"!!! Read on here under zyprexa withdrawls about what most of us feel when we are coming off of this drug. You will be surprised on what it does to someone's well being.... good luck
Helpful - 0
874521 tn?1424116797
thx for the quick reply...I will pass this on to my son...hopefully the pdoc wl make some big changes 4 him he sur isn't doing as well as we had hoped by this point!!
the extreme anxiety has stopped but this extreme depression and tiredness aren't at all good either....somehow there has to be a combination that will work better for him.
thx again, have a good day!!
Helpful - 0
585414 tn?1288941302
From what I remember Depakoate and Zyprexa both were extremely sedating for me and Depakoate in general works better on mania than depression. But its better to wait to speak to his psychiatrist before making any changes. Abilify is an antipsychotic that is the least sedating and Lamictal is less sedating than Depakoate and works better on depression. You could ask his psychiatrist about that.
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