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Bipolar Disorder Community
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766412 tn?1234896883

Seroquel for Bipolar depression?

Has anyone found seroquel to alleviate their depression? I am Bipolar 1 and just recently started taken this drug. Thanx for your replies.
8 Responses
659397 tn?1279417567
When I was taking seroquel, (quetiapine), I found it to be a really stabilising drug, I didn't have any real extremes of mood, and weirdly, never cried. My only problems were that I got very tired at times, and often got cramps in my legs, but after awhile taking it those things became less harsh. Good luck with it.

607502 tn?1288251140
Seroquel is not an Anti Depressant - it does have some limited AD properties but it will not work as a true anti depressant - its used as a mood stabiliser which may be all you need but it depends on the level of depression you have right now.

The best thing to do, as always, is ask your Psychiatrist the question - if the depression is severe you most likely need to be on an Anti Depressant as an adjunct to the Mood Stabiliser.

Dont mess around with depression - letting it go in the hope things will get better is dangerous - trust me I know firsthand.
Avatar universal
Seroquel has different properties, dependant on the dosage. It's really good for the manic phase, and there are new studies showing at higher dosages that it can be used on it's own for both "poles". Did you ask why? It's really important to find that out, the more you know as an educated consumer, the less stress you will have.

Personally it works really well for me anxiety, hypomanic moments and I am darned sure my depression. This med is great, there is a lot of flexibility in dosing, personally, and I'm not going to say this is for anyone else, if I feel really anxious, I call in a "Manic Panic", I can add an extra 50-100mgs a day during those periods of time.(with permission of my pdoc). He prefers this over taking ativan or other drugs in that class.  I am rapid cycling and mixed states. Which means my moods can flip quickly and may be cranky on top of rapid thoughts of obsessive/paranoid thinking, not just happy euphoric moods. (I actually rarely get those).

Are you on any other meds? Were you just diagnosed? It's important to get a bit more information to help you more.  When I was first diagnosed that was the med I was given, while weaning off an anti-depressant which was making me manic, what a godsend to me. It shut of my "hamster wheel" in my head. It's one of the safest drugs and considered a "front line" drug.

Keep in touch,
LCC
766412 tn?1234896883
Thanks for your responses. I think it is a mood stabilzer that I needed. I get the sleep with the Seroquel that I was missing.,no longer watching the late news till I fell asleep. Seroquel is great for anxiety and I think Clonidine has helped that also. I have been diagnosed a manic depressive since age 17. I was a senior in high school when I flipped out. I lost a lot of friends after /during the mania that lasted several months. I felt really good and really started to talk, talking way too much. I thought anything was possible. I changed from always being the quiet guy that sat in the back of the class to going into debates with fellow students/teachers. I was like an entirely new kind of animal. Some friends liked me better when high but realized something was really wrong as I progressed into insanity. I was too much at home also and my parents put me into rehab. for a good month where they overloaded me with Haldol and lithium to bring me down. I currently take an antidepressant Cymbalta 60mg., Lamictal 400mg., Seroquel 200mg, Clonodine .015mg.
Avatar universal
Hi everyone (especially the original poster),

I'm new here but I actually joined this whole MedHelp network for weight loss DUE to seroquel.  Over the past six years I've reached a high dose of 400mg, and now I'm starting to experience some of the side effects: massive weight gain, slowed metabolism, messy lipids and cholesterol levels, and a bunch of other stuff that is starting to put me at risk for Type II diabetes.  My doctor and I have been trying to wean me off of the seroquel and I'm now down to 250mg, but it has been a rough, rough road.  Yes, it's extremely helpful for putting down my manias, especially dysphoric manias.  But it's almost addictive, in a way, and getting off of it has been nearly impossible.  There are already class action lawsuits forming for the side effects I (and many others) experience.  If you can find something else that works or if you can live without it, I recommend based on personal experience that you DO NOT start this drug.  But I'm not a doctor, just a patient who's been dealing with medication ******** for ten years now.  So ask a doctor.  

I WILL say, by the way, that I'm finally on lithium (after trying nearly everything else in the book), and it allowed me to go from a high of SEVEN medications to just two (lithium and seroquel).  I really think it's a wonder drug.
Avatar universal
My husband takes seroquel and depakote. He has been on it for 10 years and has done great with it. He did change from taking morning/night to just at night due to his high dose making it difficult to function during the day.
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