Can someone tell me the prognosis for my mom's recovery based on the following these two test results?
How severe is the cancer?
What medicines/treatments can be effective in controlling/eliminating the cancer?
The doctors have recommended rediotherapy and chemotherapy.
Thanks
-Chitti
From the results section of the immunohistochemistry report:
Estrogen receptor (ER): % of tumor cell nuclei positive = 70 to 80%; Classification = Positive
Progesterone receptor (PR): % of tumor cell nuclei positive = 80 to 90%; Classification = Positive
Her-2neu: Score = 0/3; Interpretation = Negative
From the histopathology report:
MATERIAL : Modified radical left mastectomy specimen for HPE
MICROSCOPIC EXAMINATION:
Multiple sections studied from the tumor mass show cellular tumor with circumscribed margins. There are compactly arranged glands of varying sizesl some of them show papillary processes and lined by columnar epithelium. There is moderate nuclear pleomorphism, disorganization, coarse chromatin clumping and small nucleolus. Mitotic activity is highl about 2-3/10 HPF. There are focal areas of necrosis and cellular fibrosis and focla lymphoid follicles.
Section of the nipple and areola show multiple pilosebaceous glands and basal hyperpigmentation. There are multiple lactiferous ducts lined by double layered columnar epithelium.
Rest of the breast show focal acinar atrophy, patchy areas of cellular fibrosis, hyalinization. Some of the interlobar ducts are cystically dilated and lined by tall columnar epithelium.
Sections of axillary lymph nodes (0/8) show preserved architecture and multiple lymphoid follicles, germinal centre formation and intervening sinusoidal pattern. There are focal collections of pigment laden macrophages. There are free of tumor.
IMPRESSION:
Features are suggestive of invasive ductal carcinoma, histological grade II, left breast.
Fibrocystic disease with hyalinization, rest of the breast.
Nipple and areola, tissue at the posterior surface and axillary lymph nodes are free of tumor.
************* End of the data from the reports ********************