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microinvasive HER2+ grade 3

Oncologists are not sure if I should have chemo/Herceptin but will give it to me if I request it.  Had Bilateral mastectomy and trying to make good decision.  DCIS w/microinvastions that do not equal 1 mm.  What was treatment recommended?


This discussion is related to DCIS.
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962875 tn?1314210036
Hi,

Just wanted to call your attention to some possibly relevant research:

"From the San Antonio Breast Conference in December 2009, new data shows a higher than predicted rate of breast cancer recurrence even with very small breast cancers that are HER2 positive. The data is from the first large study to analyze early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller. All these women would benefit from adjuvant Trastuzumab, also known as Herceptin, (for one year, the standard in America) - along with adjuvant chemotherapy. This represents a shift in the way women with early-stage HER2 positive breast cancer should be assessed for risk of recurrence and considered for treatment, according to the study's author."

Best wishes...

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25201 tn?1255580836
Without complete Pathology report it's difficult to say if Chemo would be necessary. If your Oncology Team isn't sure we here couldn't make much of a recommendation. The cancer must have been Her2 positive for that to be considered but you make no mention of ER/PR positivity or if nodes were negative. You could get a second opinion from another Oncologist if you are having doubts regarding your treatment.  Regards ...
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