I am 35, I have had an ostomy for the treatment of my Crohn's disease for more than 14 years. Over the past few years I have taken more and more laxatives to relieve my constipation it is getting worse and worse now I am taking amiteza, miralax and otc correctal tablets every day and still I have cramping and pain, which is so severe I cant sleep. I had a colonoscopy a few days ago, in which my GI doctor told me he could find nothing wrong except maybe when my ostomy surgery was done, there could be so nerve damage in my colon, but still he was at a loss to explain why I have such severe constipation, the pain is so bad it is difficult to work or do anything but lay in bed.