My father-in-law suffered anxiety w/depression after my brother-in-law committed suicide. After many months, med's started working & things seemed better. 8 months after the death, his wife had an unexpected heart attack & died. Still on his med's from prior tragedy, he was seemingly doing well. Unknown to us, med's ended Oct 2007 & by Dec 2007 anxiety was back. This time symptoms have seemed to progress faster than last time. He has physical symptoms that we have been ruling out with the doctor for physical causes (his lack of belief that anxiety/depression is the cause). He has been on med's again for 5 weeks, but they are not doing their job. The psychiatrist has boosted & changed his med's to help speed up treatment, but so far not good. Bipolar disorder runs in his family & so does alzheimers disease. Could anxiety/depression cause these disorders to rear their ugly heads? Is there a test to determine what is neurological, psychological and/or physical? We just don't know what to think.