My doctor told me that Sertraline and Zoloft both have the same ingredients but the pharmacutical companies can make them differently. I too notice a difference in how I feel taking Zoloft vs. Sertraline. I like Sertraline better though because I don't feel as numbed out and my sex drive is not affected.
no difference. just the name. i have heard however, that sometimes the same antidepressant used for a second time after a break may be less effective. this was told to me by a physician though another physician suggested otherwise.