What can cause liver enlargement?

[helen]

Dear Dr,
10 days ago I was at my swimming class after work and felt a pain on my upper right abdomen. The day before, I noticed that my belly was swollen and I was felling pain in that area. As I couldn't identitify where the pain came from, I went to a hospital near my job and ask a doctor. He asked for a US. The result of the US is "hepatomegalia". As I'm under treatment for depression and have to take lots of medicines, I called my doctor for instructios. She doesn't think that there is a relationship with all this things and said that the liver doesn't pain. As the pain was still bothering me, I went to see a gastrodoctor. She said the pain is in fact in the liver and asked for lab tests for hepatitis (A,B,C) and liver function. She said that my liver is "very grown" and "painfull". The lab tests are all negative and the only finding is a high hemosedimentation rate. I'm following the instructions for rest these days. I want ask you this: if I don't have any kind of hepatitis, what could be the cause of this pain and enlargement? Is there a possible link between muscle weakness and this liver enlargement? Drugs to treat depression (reboxetine+paroxetine+valproic acid) can cause liver enlargement? What should be the next appropriate step after the lab tests?
Thank you very much for your attention (sorry for any English mistake)
Helen

[Shelly K.]

Crystal, I would like you to write to me about your elevated enzymes. Upon routine blood I was found to have elevated ALT of 85 And AST of 170 2-3 weeks ago. Repeat blood work showed increase of ALT to 125 and AST to 225, triglcerides of 324 and cholestrol of 235.( the last two are very elevated for me)Ultrasound showed a generous sized liver and eveything else was normal. Hep C came back neg, Hep B was questionable because of vaccine series for it. Lupus was ruled out. I have constant abdominal bloating feeling and generalized diffuse pain in right upper quadrant. My maternal grandfather died of liver cancer(70), my mother has liver cysts and her brother died of cirrhosis of liver at age 44. I am 41. I can't get into to a GI doc for 2 months and physcian doesn't feel my situation is urgent. Needless to say I am concerned. Please write-
shell_k***@****

[Crystal]

Dear Shelly,  
It sounds like a fatty liver to me.  I just seen my Dr. yesterday for more recent blood results.  ALT of 209 and AST 182.  I will be seeing the specilast for a Biopsy.  As with you I am negative on all hep test too.  I do know with the high cholestrol and enlarged liver that goes hand and hand with a fatty liver.  I also have a bloted stomach.  How frustrating.  Keep in touch with your progress. Crystal

[Iris]

To Crystal, check out pbc (primary billiary cirrhosis) for the elevated enzyme symptoms

[Crystal]

Hello,
It it wonderful to see this site.  I am 34 years old and have had elvated liver enzymes for approx 4 years.  The source is unkown.  I did however when this was first found cut everything out of my diet except green vegetables  and it worked in 3 months my levels were normal, then having a HMO I lost my doctor and had to see another.  Well I am back where I started with the exception I am worse.  My levels are high and now I am having pain in my back.  I think maybe my kidneys!  My question is has anyone experienced this?  Are there any treatments available for the treatment of evalted liver enzymes?

[Fred Kline [email protected]]

I have a swollen stomach withmild stomach pain after taking a nap in a recliner or when I get up in the morning. The symptom occurrs when I have been in a prone position for a period of 1 or 2 hours. I also have very shortness of breath with any slight exertion or activity. In some cases I can twist my shoulders to the left and this also takes my breath             After I am up amd moving around for a while the swelling resides somewhat and the mild pain goes away.
     I had triple Bypass surgery 23 months ago.
    I am presently taking 25 MG and an aspirin each morning. and an occasional Lassics with potassium if my wieght increases or ankles are puffy

[Fred Kline [email protected]]

I have a swollen stomach withmild stomach pain after taking a nap in a recliner or when I get up in the morning. The symptom occurrs when I have been in a prone position for a period of 1 or 2 hours. I also have very shortness of breath with any slight exertion or activity. In some cases I can twist my shoulders to the left and this also takes my breath             After I am up amd moving around for a while the swelling resides somewhat and the mild pain goes away.
     I had triple Bypass surgery 23 months ago.
    I am presently taking 25 MG and an aspirin each morning. and an occasional Lassics with potassium if my wieght increases or ankles are puffy