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What can cause liver enlargement?

Dear Dr,
10 days ago I was at my swimming class after work and felt a pain on my upper right abdomen. The day before, I noticed that my belly was swollen and I was felling pain in that area. As I couldn't identitify where the pain came from, I went to a hospital near my job and ask a doctor. He asked for a US. The result of the US is "hepatomegalia". As I'm under treatment for depression and have to take lots of medicines, I called my doctor for instructios. She doesn't think that there is a relationship with all this things and said that the liver doesn't pain. As the pain was still bothering me, I went to see a gastrodoctor. She said the pain is in fact in the liver and asked for lab tests for hepatitis (A,B,C) and liver function. She said that my liver is "very grown" and "painfull". The lab tests are all negative and the only finding is a high hemosedimentation rate. I'm following the instructions for rest these days. I want ask you this: if I don't have any kind of hepatitis, what could be the cause of this pain and enlargement? Is there a possible link between muscle weakness and this liver enlargement? Drugs to treat depression (reboxetine+paroxetine+valproic acid) can cause liver enlargement? What should be the next appropriate step after the lab tests?
Thank you very much for your attention (sorry for any English mistake)
Helen
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Avatar universal
I have a swollen stomach withmild stomach pain after taking a nap in a recliner or when I get up in the morning. The symptom occurrs when I have been in a prone position for a period of 1 or 2 hours. I also have very shortness of breath with any slight exertion or activity. In some cases I can twist my shoulders to the left and this also takes my breath             After I am up amd moving around for a while the swelling resides somewhat and the mild pain goes away.
     I had triple Bypass surgery 23 months ago.
    I am presently taking 25 MG and an aspirin each morning. and an occasional Lassics with potassium if my wieght increases or ankles are puffy
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Avatar universal
leo
The is a rare genetic disorder called Polly Cystic Liver that
causes the liver to enlarge by displacing it with hepatic cysts
that range in size from small to very large.  The total weight
of both cyst an liver can be significant.  I have this disorder and the weight of my liver/cysts is currently about 67 pounds
(that is not a misprint!).  I had unbearable progressive pain and
had a liver resection to turn the position of the liver; however the size is still big and I am on fluid pills for the last 3 years to keep the total size under control.  After the surgery, I have experienced no pain except in my back because I have to carry this enormous weight around.  It looks like I have been 9 months pregnant for the last three years.  This disorder is passed on through generations and someone in your family must have had it in the past (review your family history).  The only cure is transplant, but it is not a life-threat disorder in itself.  It is very rarely caught because of how similar it could be to other things and how rare it is.  More women than men are candidates for this disorder (I am male).  The internet has other data you might find usefull (keyword: polycystic liver)
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Avatar universal
Dear Helen,

My name is Tellah Taylor my email address is ***@****.  I also have an enlarge liver but no pain.  I had extensive test done the last being a hepatic angiogram and I was doagnose with hemangiomas of the liver.  I have no symtoms.

Please let me know what your doctor said.  I am in the process of having my tumor shrunk or embolize.


Good Luck

Tellah
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Avatar universal
I went to my doctor about after I eat anything I would get real ill in my stomach and she sent me to get a ultrasound done.She told me I had a diffuse fatty infiltration of the liver.Now she wants me to get a Hida scan with a eck order can you please tell what that is?
Helpful - 0
Avatar universal
Dear Gloria,
Thank you for your reply. You asked me about Reboxetine: i'm teaking it for 2 years, since its approuval here in Brazil. I have a very resistant depression and this med really helped and help me. Thank you again,
Helen
Helpful - 0
Avatar universal
Helen,
Most doctors will say that determining what causes liver enlargement or elevated liver enzymes, is a process of elimination.  As I said on my previous post, Valproic Acid is a known hepatotoxin (a drug that is dangerous/toxic to the liver).  Not everyone on the medicine will have trouble with it, but some do.  Since you were negative for hepatitis and your enzymes were normal, and the only abnormal lab test was your sedimentation rate, one has to wonder if your meds are causing this problem.  If you are anemic, or were on your period when your blood was drawn, you can have an elevated sedimentation rate.  This test is prone to being unreliable due to it being affected by the length of time the specimen sits around before being processed--usually that gives false low readings, though.  Is the ultrasound the only diagnostic procedure you have had?  Usually, a doctor will do a CT Scan of the abdomen if the ultrasound is positive.  As for your pain in your abdomen, most people experience pain when their liver (or spleen) is enlarged.  Is your abdomen "swollen" because you have fluid (ascites) in it?  Hopefully, your doctors will be able to help guide you through this process of trying to figure out what is wrong with you.  Best wishes to you and your family.  Good luck.  Gloria
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