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Can Use of Protopic lead to camcer

Hi please can someone help. Can use of Protopic in dogs eyes lead to immune disease and cancer. My Ophthalmologist is not friendly and puts me down when I ask him he says I am a worrier and worry too much.
Lately my dog has developed Corneal Dystrophy. Could this also be caused by Protopic use.my dog is a 4 yr 6 mth cavalier king charles spaniel and now coincidentally also suffers from malassezia since the use of Protopic since May this year. I appreciate any help.
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