Once a dog refuses water you have a life-threatening situation. Please waste no time in getting her to an ER vet!
I agree, dehydration can kill. take her please and let us know.
very serious, he could have injested something that is now stuck, or have any number of other things, if she is older it could be a sign of cancer. if she is not up to date on shots it could be parvo. is there any chance she ate something toxic