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Post-exercise malaise

I suffer from post-exercise malaise and fatigue three hours after, and the next day after, modest exercise, i.e., a slow 20-minute jog. or a slow swim of 8 lengths in a pool. I try to do one or the other every two or three days. My doctor doesn't know what it is, and referred me to a sports medicine doctor who did blood tests doesn't know what it is either. Is the immune system being suppressed? What can this be? Should I see an endocrinologist? It's getting in the way of leading a productive life.
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Robert: That's great. I'm envious that you may have turned a corner. I think I've had this for eight or nine years. Let me know if it doesn't last.
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The relief from malaise/fatigue didn't last ...I crashed on Nov 1 and I'm struggling 24/7.  I pretty sure this thing is virus-related since it feels like a constant flu or cold  and lots of other possibles have been eliminated. I'm running out of ideas of what to do.  The new media buzz for fatigue is XMRV virus. I'll follow that and maybe get tested for it some day.  GL to all who have this.
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I'm doubtful that this is a virus, at least any ordinary virus, when I examine my own situation, because while exercise brings this on, if I don't exercise for a few days, the malaise goes away, and I would think that a virus would persist. But I could be wrong.

From what you say, and my experience is largely the same, I think the immune systen is implicated in this and may be the actual culprit.

When I google post-exercise malaise, the first two hits are chronic fatigue syndrome, which this is not, because the malaise is temporary and transient, and chronic fatigue syndrome is not.

I'm going to be referred separately to an allergist, immunologist, endocrinologist, and internist. The latter is a general investigator. You might consider asking to be referred to an immunologist, but not any ordinary immunologist, rather someone who loves medical mysteries and challenges generally, who is infinitely curious, and who is always ready to roll up his sleeves to get to the bottom of something like this. Too many doctors don't know what it is, may check for things they think it might be in their knowledge and experience, like the thyroid, and then lose interest and give up.
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Any updates on your status?
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I am a 50 year old healthy woman who walks regularly at a fast pace without any symptoms.  However I can't do any exercise which requires my body to switch into the anaerobic mode (ie high intensity) without feeling sick the next day.  I first noticed it 15 years ago when I went to a gym for an hour. I felt sick all over for 2 days afterwards, as if lactic acid or something had built up in my bloodstream. So I quit the gym.  Last year I again decided that I needed to try weight training and it only took 5 minutes before I began to get a headache and feel dizzy.  A year later (this week) I decided to get in shape with an exercise class.  I was fine during the class, got a headache soon after, and now have been feeling lousy and tired for two days.  I just spent many hours on the internet and have come up with a possible diagnosis:  mild mcardles disease or else myoadenylate deaminase deficiency.  Neither of these genetic quirks can be cured.  My hope was that I could slowly increase my work out to keep my symptoms at bay but I am nervous to even try this because it is not worth having to stay home feeling horrible.  Actually the day after my class I didn't feel as bad as I do now, which is 2 days later.  So that is a bit puzzling.  
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Avatar universal
Sounds familiar for sure, especially headaches and feeling sickly and the delayed malaise . I had this for at least 12 months after a lifetime of athletics. I still can't pinpoint the cause after lots of tests and study.  In the last couple of months I have been doing much better. I have very gradually built up with weight training and aerobic forms of exercise. I'm hoping I will be stay better.  I guessing it has to do with losing muscle tone from aging  and rapid changing blood flow and changing blood pressures in differents parts of the body that the body isn't used to. Maybe a very gradual biuld up would work for you.   gl
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Arlington, VA
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