Yes, anxiety and depression will contribute, but I also agree with the post above. I deal with anxiety and depression myself, so I know it's only part of the picture. Do ask about this test.
One home remedy you can try is making a decoction (a way of making tea from roots and seeds) with ginger root. It is easy to make and inexpensive. It either works for you or it doesn't, but at least it isnt outrageously expensive like the Zofran is. It will be a few years more before Zofran will be covered by insurance carriers for conditions besides cancer or kidney patients.
Simply use the smallest saucepan you have. The one I have only holds about 4 cups water total. Give or take. Fill the saucepan and bring to boil. Meanwhile, cut off about 1 inch of the ginger root. Use your paring knife to peel the skin off of the ginger root. Thinly slice the ginger root across the grain. Add to the water, then simply allow the water to keep boiling until half of the water is evaporated. Remove from heat. It will work best without adding sugar, but you can add sugar if you don't like it without sugar. But, for chronic nausea, I don't advise using sugar. Also, especially don't use artificial sweeteners. I've noticed they are much more upsetting to the stomach than just natural cane sugar. Table sugar bothers me much more than natural cane sugar.
I can't use this remedy any more because of sulfite sensitivities. Ginger is a natural sulfite, as are garlic and onions. Grapes are, too.
As I deal with a lot of nausea, I thought it was worth mentioning the natural ginger tea remedy, because it's easy and affordable. It either works or it doesn't, but it's worth a shot.
This isn't to do instead of finding what is wrong, but it should hopefully help make you a bit more comfortable.
Welcome to the gastroenterology community! I would recommend seeing a gastroenterologist and asking for a gastric emptying scan to check for gastroparesis which is slow emptying of the stomach. Does your nausea get worse when you eat?