Hello~Those are a lot of drugs to take together, and I would say, it is not a good idea to try it. To be sure, I would call your pharmacist and ask them if it is harmful, I really don't know, but, I would say it is and to not do it until you find out for sure.
Cymbalta can work wonders for some people that have depression. It's one of the more stimulating meds though. Seroquel used to be used more for bi-polar but is being used more often now for depression. Did your Dr explain why they wanted you to take this med combo? I do agree with SassyLassie. Call the pharmacy because they'll know if you can takes these meds together safely. Remar