Six days ago I developed an irritation in the crease under the buttocks and then it spread to the upper inner thighs. The next morning I noticed red spots/blotches on my palms. At the same time I noticed them in my armpits, but they did not itch at all. I also have them on my ankles but only on the inner side of the ankles. They are not bumps and are not raised. Most don't itch except the ones in the crease under the buttocks and sometimes on palms of hands. There is one open raw crack in the skin in one location between two specific toes. I don't know if this is related but I have never had athlete's foot in my life. I have no genital sores. One derm says syphilis or erythema multiforme, one derm says herpes, Lupus, leukemia are possibilities. I am awaiting lab results, but I don't believe either one of these doctors. One other significant note: this is the second time this has happened. Had it first time 6 weeks ago coinciding with a very bad upper respiratory cold, but the rash symptoms were more mild than they are now, but in the exact same places, including the toe. This time I have mild respiratory like a minor cold, but the rash is much more severe. Have we overlooked anything here? What is your feeling? I am so confused because one derm wants me to take prednisone, and the other warns against that kind of treatment. No biopsy was done. What do you suggest?