I am a 48 year old male, 6 ft and 76 kg. I had Ant wall MI in August 2007 with inferior wall ischaemia. Stent was inplanted in LAD with 100% blockage. OM2 100% blockage but filled by collaterals. By december 2007 I was taking 12.5mgx2 betablocker(carvidilol), 5mgx2 ACE-I(ramipiril), Monotrate 10mgx1, Aspirin 150x1, diuteric and Clopidrogel(anti platlet) 75x1, drug for cholestrol. I was able to walk 1.5 miles (35 minutes) and do my office worl(table job) without getting tired by evening. I was taking low fat, low salt diet.My EF reached 40% from 30% post MI.
In january 2008 I had syncope event. The tests were conducted, holter test, MRI, ecocardiogram(Mid ostial LAD has 30-40% plaquing, D1 medium sized and has 60% osteo proximal stenosis, D2 large and has 80% ostial stenosis, large RV branch has 90% ostial stenosis), angiography, electrophisiology study. None could establish syncope relation to heart. But my EF evaluated by cardiologist during angiography was 20-25%(although as per ecocardiogram it was 30-35%). Due to low EF I was implanted ICD. During this one month period my beta blockers anf ACE-I were reduced by half.
My recovery after ICD was reasonable I could return to original dose of betablocker(12.5mgx2) and ACE-I(5mgx2) with adition of Aldectone(12.5 mgx1) and my walking capacity increased. In march end I started feeling some tiredness. My doctor advised me to increase beta blocker by twice(25 mgx2), Monotrate was discontinued. But I started feeling tired, I could not walk at same speed as earlier, I had strange sensation in head and throat region. I was asked to reduce ACE-I. I was told that remaining blockages will have to be managed by medicines and diet at this time.
Now for more than three weeks I am taking 18.75 mgx2 betablocker, 5mg and 2.5 mg ACE-I and other drugs as above, i.e. Aldectone(12.5mgx1), Aspirin 150mgx1), Clopidogrel( 75mgx1) and for cholestrol. My Echo report one week back shows EF 30%, LV dilation, hypokinesis of LV walls except lateral wall.LV systolic velocities are reduced.
My interraction on this forum reveled that the dilation of LV is serious issue and until it starts remodelling by drugs longivity of patient with above conditions can be in doubt. Does someone has experience with these conditions or related information which can be shared on this forum. Can LV remodel itself with beta blockers and ACE-I? I have seen remarks/suggestions from reputed cardilogists and patients who share their experiences and all this is very useful for patients like me.
My questions are:
1. Are my doses of betablocker, ACE-I and Aldectone adequate? Do I need to add any other medicine?
2. What factors should be closely monitored, pulse rate low(how much?). My present pulse rate is 70-75 bpm 60% time, 75-80 bpm 20% time and 80-90 bpm 20% time during 24 hrs. My bp is consistant 105-110/70-75? Other physical conditions and symptoms required to be monitored?? What are indication of worsening situation?
3. How much walk, at what pace is advisable?(With my present activity regime my breathing remains normal.
4. Will my condition improve, EF, Hypokinesis of LV walls and LV dilation remodelling??
My thanks in advance to everyone who responds.