i was having heart paps alot, first i thought it was changing to a natural thyroid, or maybe my estrogen was too high but i changed meds and they only got less.......so then i started burping alot i noticed and went off the digestive enzymes....AND ALL HEART PAPS VANISHED........not one night or day.......and i was having them first thing in the morning evening during the day.......way too many but i knew it had to besomething i had done recently...and thankfully it was.......so always look at the meds you are taking....and try one by one to see if any make a difference....