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Are there any medications or therapies which INACTIVATES THE HBV cccDNA

I would just like to know if anyone here in the community have any research which relates to the approaches in which the cccDNA can be blocked/destroyed/inactivated/interfered since from some of the forums here the culprit to the persistence of the virions and the surface antigen would be this cccDNA template inside the hepatocyte? is it in the cytoplasmic area or in the nucleus of the liver cell?

Have you found out any herbal medicines or any drugs which can block this template? please share your research regarding the cccDNA. thanks.
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Avatar universal
ALso, I did I keep running into recent in vivo studies with phillanthus against HIV and how it is extremely effective in lowering VL.

That shows how it is widely studied for its anti-viral abilities!



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Avatar universal
I am still waiting for them to come in. Please recommend a place to upload the image.

--Scan your lab results with some parts covered for your privacy, then upload them to your photo album section, then provide their links in your postings as you dicuss them.  See examples in my threads.
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Avatar universal
Well if it worked this good for me, maybe there is some one else out there it can work for, perhaps with my recommended method, frequency and strength it will work for others .

The results are dramatic! From Jan 09 to Mar 09 to go from over 10 Million down to 300 thousand viral load. What more proof do you need with a 97% reduction in VL?

If there is a possibility that something may work, but did not, I never felt like it was a waste even if I paid a lot of money for it. I am not rich at all! Things that did not work I gladly scratched off the list knowing I did my best and tried.

Extra Virgin coconut oil. Too hard to eat as its gross to eat oil. Capsules are ok but I wanted quick results. There was no dramatic decrease in VL the time period I was taking this.

Inconclusive: Parasite cleans: I read that most people some form of parasite from Tape worms to small liver fluke parasites that are like virus factories. Eliminating viruses alone may reduce it from your body but not completely if you have parasites. Again human parasites are disgusting yes, but also common.

I did a cleanse taking Black Walnut, Wormwood and Clove nothing came reduction did happen but I was still taking the Chanca Piedra tea.

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Avatar universal

i also read wrong at the begining reading tea and vitamins and probably overreacted seeing a website address in the post
we know phillanthus,i even try to order it with liquorize because known to be active on hbsag/hbeag and very little on hbvdna and made some posts in the past about it.

a chinese member told me it doesn t work, nobody got hbvdna und and normal alt in the trials, it might work for some people and that is good but definitely it doesn t work on many people or very potent, a combo with phillanthus, ntz and a nuc maybe more active on hbsag while nuc on hbvdna

the results of trails on phillanthus amarus i posted in the past, it is under novel treatments but the trial is of poor siginficance, hbvdna suppression -3log copies is very little usually 3 log can be even monitored only:

https://docs.google.com/fileview?id=0B_yFgxI8KNcRZjQyZTBjZWItY2FjZS00NDIxLWJhNDAtODMzZTkyM2Q0NDJl&hl=en
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Avatar universal
I am still waiting for them to come in. Please recommend a place to upload the image.

I cant believe he would say that vitamins were useless and that they had no benefit against HB. That tells me more research is needed on his part.

In fact to post that when others come here looking for suggestions was, well...
Not good!

Antioxidant Therapy. As with other diseases related to inflammation and tissue damage, oxidative stress is a key mediator that continues and magnifies the ongoing disease process. The livers of people who have hepatitis show reduced levels of antioxidants, which are consumed in an effort to protect the liver. According to a report in the June 1998 issue of the Journal of Clinical Gastroenterology, investigators showed that nutritional antioxidants are potential therapeutic agents for diseases such as hepatitis. Other investigators reported at the same time that oxidative stress (free-radical damage) is often seen in hepatitis B and may contribute to the emergence of hepatocellular carcinoma, seen in patients after years of chronic liver inflammation. The study stated that antioxidants that down-regulate oxidative damage may be a useful complement to specific antiviral drugs in the therapy of viral diseases.
In a related study, vitamin E (alpha-tocopherol) was reported in a randomized, double-blind, placebo-controlled study to be a successful adjunct approach when combined with alpha-interferon therapy in the treatment of hepatitis because of its strong antioxidant activity (von Herbay A et al 1997).
Selenium. The protective role of selenium against HBV was reported in 1997 in the journal Biological Trace Element Research. The study reported that, in areas of China with high rates of hepatitis B and primary liver cancer, high levels of dietary selenium reduced the incidence of liver cancer and hepatitis B infection. In a 4-year trial of 130,471 people, those who were given selenium-spiked table salt showed a 35.1 percent reduction in primary liver cancer, compared with the group who received salt without selenium. In the same journal report, another clinical study of 226 people who tested positive for hepatitis B showed that taking a 200-mcg tablet a day of selenium reduced the incidence of primary liver cancer to zero. Upon cessation of selenium supplementation, the incidence of primary liver cancer began to rise. The study seems to indicate that taking selenium on a continuous basis is beneficial to people who have viral hepatitis (Yu SY et al 1997).
These human trials have been duplicated in animal studies. The animal studies showed that selenium supplementation reduced hepatitis B infection by 77.2 percent and precancerous liver lesions by 75.8 percent.
Another study in the Journal of Trace Elements and Medical Biology reported the role of trace minerals in diseases such as liver disease and hepatitis. The report indicates that, while there is still some debate regarding the specific role of trace minerals, minerals such as selenium and zinc are of benefit to those who have diseases such as hepatitis (Loguercio C et al 1997).
A 3-year study of 20,847 people investigated whether supplementation with sodium selenite could prevent hepatitis B. The researchers concluded that: "The incidence of virus hepatitis infection in the test population was significantly lower than that of controls provided with no selenium" (Yu SY et al 1989).


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Avatar universal
That stefano170669 is not Big Pharma but an authentic HBVer just like you is written in all corners of this forum.  It is also beyond any doubt that he has done serious learning of the Western medical way of dealing with HBV, is using it on himself and is using his knowledge to help others which we should all appreciate.  It would help clear his doubt on your tea treatment if you could scan and post some of your lab results.
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