Can I stop Viread after 8 years ?

[Mechino]

I have been on viread for over 8 years and each time the virus is always negative in the blood ( DNA < 20 )but now hbsag = 11,000,000 UI/mL recently and I have been taking this viread everyday. Today my kidney is showing serious sign of weakness « creatinine-117umol/L and 13,2mg/L. CKD-EPI -67. DFG afro-américain - 78) can i stop viread now because it is damaging my kidney seriously ? My problem is my doctor continue to give me a smile that all is well knowing fully well that i’m dying !!! Please again can I stop VIREAD in this my horrible condition?

[Mechino]

In 2007-2008 I was treated with pegasys and I remembered that at the end of 12 months therapy my hbsag was 100 UI/mL but I lost my previous doctor so I got this new doctor since 2008 who placed me on viread from 2009 . This volume of hbsag 11,000,000 UI/mL scares me a lot and my kidney.. I hope this hbsag can go down.

[Jatashankar]

Ohh no that's drastically sad to have such a huge rise from such a low level of hbsag. U could have continued ifn that time a couple of more months.

[Mechino]

Yes i also remembered that I was developing antibodies against hbv but the volume was very little. This my new doctor told me to switch to viread simply because the dna was positive but the hbsag was 100 . Today my hbsag is 11,000,000 and the virus remains negative. I think viread is not a good treatment for hepatitis b since it can  increase hbsag.

[luckyman316]

hbsag = 11,000,000 UI/mL ? Is that number right? That seems awfully high.... were you at an acute stage at some point when they decided to start meds?

[Jatashankar]

No don't stop viread and wait for a couple of month till taf arrives completely in market and then switch to it as is renosafe. Stopping viread will flush ur 8 years of virus control and chances to lose hbsag in future may go in vane.