GS-4774

[djxpress]

Has anyone heard anything about Gilead GS-4774?  This is a Tarmogen T cell immunity stimulator.  

[NewlyDiscovered]

Hi Stephen

Just curious, how is a 'vaccine' GS-4774 different from a standard hbv vaccine that is used to immunise a person?

Thanks.

[StephenCastlecrag]

Thank you for posting and hope that you will qualify for the clinical trial. It is a pity that quantitative HBsAg assay is not yet commercially available in the State, together with hbvdna, it can lead to a better stopping rule for taking oral antivirals.
Please keep us posted.

[bojubo]

I went for the screening phase today and await for test results. Hopefully everything is good to go so I can qualify for the study. Been on adefovir and entecavir since 2005 and wonder if I'll ever be off antiviral medication.

[veteranB]

Dont worry about it. This is a vaccine. I dont think anything bad can happen.

[StephenCastlecrag]

Thank you for posting. GS-4774 had undergone a phase 1 trial and the results were presented at the recent AASLD meeting:

http://www.natap.org/2013/AASLD/AASLD_74.htm

Please keep us posted if you do decide to join the trial.

[helen50]

Ive been asked to be part of this study for Phase 2. I am scared about the side effects of this. I have been on Barraclude for 4 years and dont know when I will be take off of it. Thank you.