HBeAg positive to negative

[bollux]

Hi,

I have Hep B for 16 years now (im now 30 years old), receive it from blood donation... Never mind that now. From 2004-2008 i received Lamivudine therapy and my liver enzymes got down to reasonable limits. They stayed there for 5, 6 years until my last blood control. Here is chronological results;

2008: AST 33, ALT 30, ALP 70, GGT 17, UBIL 10
2010: AST 42, ALT 46, ALP 66, GGT 16, UBIL 11
         HBsAg pos.>250 IU/mL, Anti-HBs neg, Anti-Hbc total positive,
         Anti-HBc IgM neg, HBeAg pos, Anti-HBe pos, HBV-DNA 791 IU/mL
2011: AST 32, ALT 47, ALP 76, GGT 19, UBIL 11
2012: AST 35, ALT 56, ALP 66, GGT 21, UBIL 15
2013: AST 72, ALT 156, ALP 59, GGT 24, UBIL 11
         HBsAg pos.9755 IU/mL, Anti-HBs neg, Anti-Hbc total positive,
         Anti-HBc IgM neg, HBeAg neg, Anti-HBe pos, HBV-DNA 5.45e+7 IU/mL

From what you can see my HBeAg turned from positive to negative and my liver enzymes and HBV-DNA started to raise.....

I'm waiting for specialist check in a few week but want some advices or opinions from any experiences, maybe...

Thank you all in advance..

[fred_fred2013]

1392 iu ml hbsag quantification
hbsag 3,165

[fred_fred2013]

1392 iu ml hbsag quantification
hbsag 3,165

[ank796]

How long it will take to get result of HBsAg into Negative after taking Tenofovir. If the HBV DNA Quantity UI/ML drops from 7.03x10 ^6 to 6.72x10^4 in one month.

[juanchodiego]

Kumusta experience mo sa Pginterferon??? any side effect experience???

[stef2011]

plts 52 is not sufficent to lower pegintf dose, you can reach 20-25 or use drugs to increase plts instead of lowering intf dose.135mcg dose has much lower chances of success

these are of course good being on intf whty dont you discuss the dose with your specialist or check with another intf experienced specialist too?

my last  wbc  is 3.24 si units
platelet is 92
neutrophils 16.70

[Magda123]

Fred, when you started interferon, how was your hbeag +/-, hbeab+/-?