double check harpagoside content because the effect is thanks to this and if too little there s no effect
http://www.altmedrev.com/publications/13/3/248.pdf
it is ok for hbvers, it has no sides effects at any dose or length of taking and dose is about 1.5g per day, it has very potent antioxidant effect too and it is a common vegetable to eat directly in many countries
my father uses one from germany, doloteffin, active aragospide 400mg, he takes 3pills per meal 3 times a day.it takes time to work, about 4-6 weeks and after taking it for a year my father stopped with no back pain again.
he used diclofenac sodico 1,00 mg. injections with dangerous sides effects, especially on brain function and once we read the box and warning of death on people with previous stroke or cardio problems we never used it again