Hepatitis B - Biopsy

[Neil888]

I am 31 year old Indian born male currently residing in US.
I have been diagnosed with Hepatitis B earlier this year (Feb 2013) by a screening test.
I had taken Hepatitis B vaccine back in 2007 before coming to use (3 shots), hence it looks like i got infected before that.

My results are as follows.
Date : March 4, 2013
HBV DNA - 1130 IU/ml
ALT - 30 ( Lab reference rage - 0 to 60)
AST- 24  ( 0 to 40)
HBeAg -Ve, Anti Hbe Positive
Date : April 8, 2013
AFP - Not detectable
Lever Ultrasound : Liver is unremarkable ( Normal result)

The HBV DNA and ALT, AST repated after 3 months.
Date : 3 June 2013
HBV DNA - 2590 IU
ALT - 41 ( lab Normal range 0 to 65)
AST - 26

I am really freaked out since my DNA is higher and ALT is also higher.

I met the doctor this week since I was concerned about elevated HBVDNA and ALT values. I requested doctor to have a liver biopsy. My doctor told me that he is not too much concerned with increased DNA and ALT values. He thinks to wait for next three months (for next set of HBVDNA and AST/ALT Tests) before biopsy, and told me if it remains persistently elevated, we may do biopsy. We do not have Fibroscan machines.

Can you please advise on waiting for biopsy for three months?

Also, My doctor told me that ALT seems normal, I have doubt on that as well. Any thoughts?

I really appreciate you insight.

Regards
Neil

[Soflab]

Neil any result for your genotype, fibroscan, HBSag Quant.

[Soflab]

Stef according to your findings above i need to wait to get the HBSag quant and other tests fibroscan and gynotype in order HBv or HBSag can be classified as active or dormant. As i am a seaman and on board right now i will be able to get those test done by end of august, but as red in one of the post here talks about HBC Test pos= acute and neg = chronic do i have to do this or can i be concidered chronic since i am over 6 months period and HBV didn t clear since 12/12/12therefore i can be concidered chronic carrier.
-Is it correct when we say active = either chronic or acute that it clears itself depends on tests result.
-dormant: means only chronic

[Soflab]

Alya look at your post i am a seaman as well and just compare your readings with mine. I was hired  even with HBV virus.

[Soflab]

May God bless and cure you stef for the effort you put researching all the info.

[alyaspogi]

My hbasg is 410.9
my anti hbe is 700+
i th this is chornic is this posible to be non reactive?im aplying aboard.the doctor unfited me.

[stef2011]

there is a study just posted look for it on the board

hbsag level depends on genotye for genotype D hbsag around 1000iu/ml but genotypes a,b,c require much lower hbsag.

hbvdna less than 2000iu/ml, alt less than 30 men 19 women, fibroscan less than 6kpa