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Korea Phase 4 trial - Therapeutic vaccine + inteferon

Study of Therapeutic Vaccination With Intensified Schedule Plus Pegasys Dual Therapy on Chronic Hepatitis B Infection (E+VIP)

Location : Seoul National University Hospital, Korea

Link : http://clinicaltrials.gov/ct2/show/NCT02097004
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Avatar universal
It seems this vaccine (Euvax B) contains HbsAg.

http://www.lgls.com/prod/product_view.jsp?ke_gubun=EN&prod_seq=43
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Avatar universal
the best vaccine type must contain hbcag, can you check that?

it is hbcag to be immunogenic and not hbsag, to clear hbv it is also needed more hbcab than hbsab
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I'm not sure the rationale behind this vaccine but it is in Phase 4. There must some good reasons. We could email the person conducting this trial for more info.
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Yeah, Im wondering whats the idea behind this too, I mean you are already loaded with HBsAg anyway so what does the vaccine bring ?
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This is rather interesting, I wonder what is the rationale behind it. It is ETV (HbeAg negative with undetectable viral load) with PegIFN with standard 4 dose HBsAg vaccine .
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