Long time efficacy of TENOFOVIR

[soa923]

Tenofovir is very effective in the treatment of chronic hepatitis b   Hbeag negetive patient , but my concern is that I want to find out the efficacy and safety of tenofovir in chronic hbeag negetive patient since most patient need treatment for life time 1) say efficacy for 20 years without causing any other damage to vital organ like kidney and probably any hope of hbsag loss or good viral suppression and improve liver condition and fibrosis regression

[Aduiski]

Stephen are you talking here about this particular research with regards to start-stop reduction of hbsag?

Interruption of nucleos(t)ide analogue therapyin HBeAg-negative chronic hepatitis B - a newconcept to achieve HBsAg reduction?

[Jatashankar]

"univeral vaccination has made hbv disappear in italy/european good healthcare countries"
That is also a cause for drug companies not making cure or pricing them very high. Older patients are dying newer incidence are reducing leading to lower prevalence hence demand supply and inflation comes in scene.

[stef2011]

hbv is harmless when treated correctly like most of us is doing here and even when compensated cirrhosis is reached because it will regress to normal liver

the problem is not treating and reaching decompensated cirrhosis but even then liver transplant saves life.it is all a matter of good healthcare systems when hbv/liver function is routinely checked.hbv is also unknown in generation next to mine since univeral vaccination has made hbv disappear in italy/european good healthcare countries

[Jatashankar]

Ya I wud also not say this virus harmless coz in my knowing one of my friend lost her life due to fulminant hbv. Also a guy who lost life to hbv at 35. Hbv is said harmless as it do not causes any disability in life quality until cirrhosis at late stages unlike other viruses like Ebola and h1n1 which are highly fatal at short term outcomes. Any way hbv should not be termed as harmless coz somehow it is damaging the liver either on its own or via immune mediation. It's presence is an omen.

[luckyman316]

Jason, I think it would be great to hear what side effects you had from everything. As everyone else has said, we can learn from each other and help each other avoid or combat any debilitating side effects for anything.

I'm sorry to hear your friend lost her life during treatment. That typically is not common. Was it the treatment that took her life or was it the disease itself? How far into this was she? Was she in End Stage Liver Disease?

Almost everyone worries about this disease every day, who have it. We pray and hope for a cure!

[stef2011]

I ve read stem cell treatment

this field is still in the early stage i dont think this can be useful to us at all, maybe we get some results on cirrhosis in the following years