Targeting mitochondrial dysfunction can restore antiviral activity of CD8 T cells

[landloper]

Link to the full document: http://pdfsr.com/pdf/targeting-mitochondrial-dysfunction-can-restore-antiviral-activity-of-exhausted-hbv-specific-cd8-t-c

Any thoughts on this?

If one were to try this on oneself, any ideas on what dosage one might try if not the normal dose?

[stef2011]

i use mito Q from very long time, no effect on hbsag but i also use tenofovir maybe stopping tenofovir it would be possible to check how CD8 Tcell work but i am not willing to take these risks.i ll read the paper later today interesting anyway

[landloper]

What dose have you been taking?

Why do you think that tenofovir may inhibit the effect? (I would have thought it would help the effect)

[stef2011]

10mg daily as antiage

i think it hides most of the virus from immunr system, stopping tenofovir after many years of treatments leads to hbsag loss in a percentage of patients independently of any mitochondrial antioxidants, so letting free some low virus may help immune system

[stef2011]

anyway i think percentage of hbsag loss would be low anyway, better wait for drugs to clear hbsag

[landloper]

Did you read the paper on mitoq that i linked to above though? I know it was only in vitro, but the results seemed pretty interesting to me. Do you think so? (I see you do some research on hbv)

[stef2011]

no just check all latest research, in vivo it doesn t work on me, hbsag stable on tdf

[landloper]

(you can buy MitoQ online easily. The other thing they mention is only available for laboratory use)