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anti-hbsag = 565.89, am i infected?

Sorry if i do not write correctly my question english is not my first languaje but unfortuntly i did not find hepa b forum in spanish. Im waiting for hb adn results, my surface antibody results (anti-hbsag) were  565.89 I got the hvb vaccine 13 years ago and i do not have any simptoms. Having these levels of antibidoes, can be possibly that the surfase antigen (hbsag) will positive and if it is possibly what will be the    diagnosis of this results?
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Avatar universal
All of us in this forum are not doctors, i strongly recoemend you to go with an specialist to start tratment.

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Avatar universal
I have hbs any doctor here
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Avatar universal
I have + hbs if anyone good doctor here pleas tell me what to do
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Avatar universal
If I remember correctly, under 2000 is considered no need for treatment.
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Avatar universal
Do you know where can I get information about DNA levels? Which viral levels of DNA are considered "normal" on the quntitative PCR test?

I heard that on a vaccined person, a little qtys of virus will be present for many years that can be only detected by PCR, any comment about this?
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181575 tn?1250198786
I second Nash.

As for me.  I've been treating for about 2 years now with antiviral(s).  Like most, I was anxious, fearful, and depressed when the HepB truck fell on me and I didn't have a clue what it meant.  I never had specific symtpoms of hepatitis.  Knowing makes a difference because I have a new found respect for my liver.  I know I am better.  3 million DNA vs UND.  UND is better :)  And in the beginning, I comb through alot and learned alot.  Because of the info here in the forum (and HR), I really feel like I am way ahead of the treatment curve.  Maybe 2 -  3 years from now, when the FDA standarizes my current treatment, sheesh...what old news.

Also if I was your wife, I would ask to redo the DNA, quantitative this time so she will get actual viral load numbers.  Just to rule out unlikely scenerios.  Good luck.

And yes, keep us heppers in your prayers.  Thanks.
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422881 tn?1257603579
Glad to hear that your HBsAg is negative. From what I can tell, all of your results look GREAT...except for the DNA being positive.This makes me wonder if the DNA test was a "False Positive".

You may want to have them re-test the HBV DNA...especially since there seems to have been some other mix ups with the lab.

False Positive don't happen often, but they can and do happen. Hopefully this is the case with your test and a second test comes back negative.

Thanks for your prayers and I wish you and your wife all the best.

Let us know if you find out anything else about the DNA test.
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Avatar universal
Today we got the hbsag and hbeag both were NEGATIVE, this results as i know  my wife is not infected with hep b. Still are concerned why pcr for hep b was positive? Any clue?

You do not know how my wife and I want to thank you for all your comments please be sure that I will be prying for all of you and your families.
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Avatar universal
Thanks a lot for you comments, we are prying every day, our kids need us and we would like to live a long long life.

Are you taking medicines for your chronic hep b? since when? Are you getting better ?

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181575 tn?1250198786
I saw that HR answered your other post.  Testing the HBsAg would clear things up alot.

In the unlikely event that her HBsAg is also positive and has chronic HepB, it's the norm not have any symptoms.  Most of us, chronic heppers don't experience any symtpoms.  Many individuals with chronic HepB never know it and live long full lives.  Of course knowing give you a chance to take better care of yourself and further improve your odds of living a full long life.
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Avatar universal
I just read yesterday an article indicating that after vaccine a very little hep b virus will be present all time coexisting with high levels of antibodies and article said that is common to happen a positive Pcr in vaacined people, the argument is because at the end vaccine shots are very little virus qtys.

Being pcr test so accurate very little virus can be detected, and normal test for surface antigen could be negative

But additional test should be performed, like anti-hbc, hbeag, hbsag and having this results the quantitative pcr should be performed.

My big concern is if she will be hep b positive and assuming she is chronic why she doesn't had any symptom in 45 years and liver and other levels are ok?
  
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181575 tn?1250198786
NashPred pointed your post to me and asked if I had anything to add from my experience.  I also notice you posted to HR, keep your eye for his response since he is THE expert.

From the labs so far, I agreed your wife's doctor that your wife have HepB.  It looks like her doctor ran the HepB DNA, QL, PCR which just tells you if the virus is detected in her blood.  In her case it was detected.  This QL PCR doesn't give the acutal numbers or viral load.  For the actual numbers, you need the quantitative PCR.

The confusion is because her HBsAb is also positive.  It is possible to be both HBsAb and HBsAg positive and be chronic infected.  There are many manifestation of HepB, and this is one of them.  I am sure about this because I am also positive for both.  I don't understand why your wife's doctor didn't test for the HBsAg.  Probably they assume since the HBsAb is positive, the HBsAg is negative.  That's what they assumed for me and they were wrong.  (I could have attended to my infection much earlier if they did the right thing.)  Even if your HBsAg is negative, as long as DNA is detected, the virus is there.  I think these are referred to as occult infections.  It could be that the HBsAg mutated somehow and shows as negative on the test but the virus is actively replicating.  In these case, the HBsAb as we know is pretty much useless.
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Avatar universal
yes we will be at lab next week to take the hbsag.

does any body know what PCR for hep b detects when is positive?

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422881 tn?1257603579
It is good news that the Fibromax test results appear to be ok.

From what I understand, Anti-HBs and HBsAg can coexist in less than 5% of chronically infected patients and may indicate the presence of viral escape mutants. If your test for HBsAg comes back positive along with your already high titer of anti-HBs, this could explain what is going on here….but I am not sure and can only guess.

Remember that all of us on this forum are just patients too, so we can only make suggestions and help you to make an educated guess at what is going on with your case….but nothing is better than the advice of a good doctor who is knowledgeable about HBV and your particular case.
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Avatar universal
Read HR's input here:

http://www.medhelp.org/posts/show/81681?post_id=post_3544558

Addresses your question directly.
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Avatar universal
about fibromax, doctor said that apparently everything is ok with liver but she is going to ask about numeric levels with lab to be 100% sure.

About pcr, with a positive result she indicate that virus is present, my big question here is  why virus and antibodies are present? I read an article about this and what I understood it could be a crhonic hep b. I really confused since no liver demage is present and ast and alt are ok.

Does any bodie know about surface antibodies and hep b virus coexistence?
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422881 tn?1257603579
I will also agree about the confusing results.

The HBsAg test is a key piece of the puzzle in diagnosing HBV and the most basic. I am very surprised that from of all the tests that you have had, this is the one result that is missing. It almost seems like they are running all of these test in the reverse order that they would normally be run.

I can’t help but wonder if the PCR test may have been a false positive. It does not happen often, but something is confusing here somewhere.

I am not sure how to read Fibromax results but I’m guessing it is ok. What did your doctor say about the Fibromax results?


Please let us know what your doctors find out and if you ever get the HBsAg result. I’m sorry it is taking so long to get the answers you need from your doctor and I know it is weighing on your mind and causing you stress. I hope you get the answers you need soon.
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Avatar universal
we do not have the hbsag results, doctor is asking now for this test and for hbcag and hbeag.

What will be the diagnosis if this 3 antigens results a positive value and the surface antibodies is > 500?

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Avatar universal
From your posted results it seems you are in the process of clearing HBV from your system by developing anti-HBs, particularly if it is the case that you just recently was tested positive for HBsAg within 6 months or less.
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Avatar universal
I just post the lab tests and upload in my photo section.

Let me know if you can see them and if not, let me know how can I share with you.

let me know your comments.

Thanks
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Avatar universal
I agree, your results are really confusing.  Is it possible to scan your lab report with your name etc covered and post it in your photo section?
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Avatar universal
I'm more than confuse now.

Today we got the fibromax results and the PCR for hep b.

Apparently the lab did not made the right test because they were asked to perform the PCR DNA test for hep B and they just get the PCR withe the following result:

PCR VIRUS OF HEP B: POSITIVE

I'm confuse because the antibodies indicates 565.89 of anti-hbs, how can interpretate this???

The positive is because she is really infected?? or can be positive because the vacine??

Any help would be appreciatted.

By the way, those anybodie can interpreteate the following fibromax results?

FIBROTEST     (F0) SCORE 0.19
STEATOTEST  (S0) SCORE 0.29
ACTITEST        (A0) SCORE 0.04
ASHTEST        (H0) SCORE 0.02
NASHTEST     NO NASH, SCORE 0.25
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Avatar universal
If so, you may be developing anti-HBs and clearing HBV, which is very good.
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Avatar universal
No.

When I say anti-hbs I'm refering to antibodies for the Surface Antigen.

The laboratory told us that blood test that they perform was antibodies, and the result was 565.89 mIU/ml

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