Aa
Aa
A
A
A
Close
Avatar universal

anti-hbsag = 565.89, am i infected?

Sorry if i do not write correctly my question english is not my first languaje but unfortuntly i did not find hepa b forum in spanish. Im waiting for hb adn results, my surface antibody results (anti-hbsag) were  565.89 I got the hvb vaccine 13 years ago and i do not have any simptoms. Having these levels of antibidoes, can be possibly that the surfase antigen (hbsag) will positive and if it is possibly what will be the    diagnosis of this results?
41 Responses
Sort by: Helpful Oldest Newest
422881 tn?1257603579
I will also agree about the confusing results.

The HBsAg test is a key piece of the puzzle in diagnosing HBV and the most basic. I am very surprised that from of all the tests that you have had, this is the one result that is missing. It almost seems like they are running all of these test in the reverse order that they would normally be run.

I can’t help but wonder if the PCR test may have been a false positive. It does not happen often, but something is confusing here somewhere.

I am not sure how to read Fibromax results but I’m guessing it is ok. What did your doctor say about the Fibromax results?


Please let us know what your doctors find out and if you ever get the HBsAg result. I’m sorry it is taking so long to get the answers you need from your doctor and I know it is weighing on your mind and causing you stress. I hope you get the answers you need soon.
Helpful - 0
Avatar universal
about fibromax, doctor said that apparently everything is ok with liver but she is going to ask about numeric levels with lab to be 100% sure.

About pcr, with a positive result she indicate that virus is present, my big question here is  why virus and antibodies are present? I read an article about this and what I understood it could be a crhonic hep b. I really confused since no liver demage is present and ast and alt are ok.

Does any bodie know about surface antibodies and hep b virus coexistence?
Helpful - 0
Avatar universal
Read HR's input here:

http://www.medhelp.org/posts/show/81681?post_id=post_3544558

Addresses your question directly.
Helpful - 0
422881 tn?1257603579
It is good news that the Fibromax test results appear to be ok.

From what I understand, Anti-HBs and HBsAg can coexist in less than 5% of chronically infected patients and may indicate the presence of viral escape mutants. If your test for HBsAg comes back positive along with your already high titer of anti-HBs, this could explain what is going on here….but I am not sure and can only guess.

Remember that all of us on this forum are just patients too, so we can only make suggestions and help you to make an educated guess at what is going on with your case….but nothing is better than the advice of a good doctor who is knowledgeable about HBV and your particular case.
Helpful - 0
Avatar universal
yes we will be at lab next week to take the hbsag.

does any body know what PCR for hep b detects when is positive?

Helpful - 0
181575 tn?1250198786
NashPred pointed your post to me and asked if I had anything to add from my experience.  I also notice you posted to HR, keep your eye for his response since he is THE expert.

From the labs so far, I agreed your wife's doctor that your wife have HepB.  It looks like her doctor ran the HepB DNA, QL, PCR which just tells you if the virus is detected in her blood.  In her case it was detected.  This QL PCR doesn't give the acutal numbers or viral load.  For the actual numbers, you need the quantitative PCR.

The confusion is because her HBsAb is also positive.  It is possible to be both HBsAb and HBsAg positive and be chronic infected.  There are many manifestation of HepB, and this is one of them.  I am sure about this because I am also positive for both.  I don't understand why your wife's doctor didn't test for the HBsAg.  Probably they assume since the HBsAb is positive, the HBsAg is negative.  That's what they assumed for me and they were wrong.  (I could have attended to my infection much earlier if they did the right thing.)  Even if your HBsAg is negative, as long as DNA is detected, the virus is there.  I think these are referred to as occult infections.  It could be that the HBsAg mutated somehow and shows as negative on the test but the virus is actively replicating.  In these case, the HBsAb as we know is pretty much useless.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis B Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.