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hbsag quantity


today i received my hbsag quantity which is 250iu/ml, if i only knew about this before starting therapy we would have choosen interferon since etv has little/no impact on this.

interferon leads to hbsag seroconversion when hbsag is less than 1600iu/ml which is the level of inactive carriers, etv has almost no impact on hbsag and cccdna eratication so it was a wrong choice.

i will keep monitoring and taking sun to increase vitamin D level which might have helped on hbsag level and wait to receive and start alinia which has a proven impact in lowering hbsag

i do suggest to check hbsag and although it is rare on cronic hbv to have it lower than 1600iu/ml (on cronic is usually 3000-10000) but it is better to check it so correct therapy can be choosen from the begining
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Avatar universal
Dear Stefano,

how are u? hope u are fine and everything is going well.

i'd like to ask re interferon treatment on hepatitis b.

im very cared when i read the side effect for interferon therapy. based on your experience, how bad is the side effect? i do more concern on the emotional side effect? what can happened?

my bottom line is, can we keep working during the treatment? can we have a normal working life? im very scared, please help me.

many thanks
Helpful - 0
Avatar universal
im asian girl.. i found out i have hep be when i made some blood test.... im a hbsag possitive... then i do to my doc for more info.. she said i should under go dna test.. so i have it... sorry i dont bring my copy here.. but the dna test result is i have 1thousand virus out of 110 thousand..ul something.. then the other virus is i have 9thousand out of 950 virus... my sgpt is 20 so pls answer my question... im going to USA... soon as fiancee visa do they have the screening of hep b? and what is all about that test i have.. am i worse? pls help...
Helpful - 0
Avatar universal
im asian girl.. i found out i have hep be when i made some blood test.... im a hbsag possitive... then i do to my doc for more info.. she said i should under go dna test.. so i have it... sorry i dont bring my copy here.. but the dna test result is i have 1thousand virus out of 110 thousand..ul something.. then the other virus is i have 9thousand out of 950 virus... my sgpt is 20 so pls answer my question... im going to USA... soon as fiancee visa do they have the screening of hep b? and what is all about that test i have.. am i worse? pls help...
Helpful - 0
Avatar universal

being hbeag positive you have more chances to clear hbv on interferon plus tenofovir

to know your status you need hbsag quantity in iu/ml and not hbvdna

do not wait to become hbeag negative because when it happens the virus has mutated and you have less chances to clear hbv on therapies
Helpful - 0
Avatar universal
I am 21, and HBV reactive. I am diagnosed with HBV last 2007 when I was in a nursing school. Unfortunately, I need to change degree and school. My last lab result was 2009.

here are my results:
HBeAG - positive (4.84) TV Negative (0.10)
Anti_HBe - negative (0.95) TV Positive (0.40)
HbsAg - Positive (15.22) TV negative (<0.13)
SGPT - 72 U/L normal range 24-54 U/L
HBV DNA Result - 4,021,537 IU/ML

Can anyone help me interprete these results, and what should I do?
Helpful - 0
Avatar universal
my hbsag quantitative
  cut of value 0.05 IU/ml
  patient value 19 IU/ml

test is performed on the fully automated and integrated Abbot Architect Ci8200 system utilizing
Chemiluminescent technology. The assay has a sensitivity of <0.05 IU/ml. The numerical value of the
patient’s result represents viral load and can be used to monitor therapy for hepatitis B.

Please help me with the interpretation
Helpful - 0
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