Aa
Anyone want to see a great article?
http://www.natap.org/2012/HCV/072712_01.htm
Here is a summary of what Gilead is doing in it's atempt to get 7977 to market but in addition, it's attempt to go for the holy grail of creating a once a day pill for all genotypes. They say in this article that they are very close. I believe them. I'm been involved in one of their clinical trials and this company literally brings tears to my eyes in how ethical and just plain decent they are in the way that they are treating patients. so, here's a good one to give everyone the hope that a side effect free once a day pill is coming that can cure all genotypes. It's coming..
Here is a summary of what Gilead is doing in it's atempt to get 7977 to market but in addition, it's attempt to go for the holy grail of creating a once a day pill for all genotypes. They say in this article that they are very close. I believe them. I'm been involved in one of their clinical trials and this company literally brings tears to my eyes in how ethical and just plain decent they are in the way that they are treating patients. so, here's a good one to give everyone the hope that a side effect free once a day pill is coming that can cure all genotypes. It's coming..
I do hope so too, but the drug they are testing, GS-5885, is too new at phase 1. Do we know if it has bad side effects, causes cancer, etc?
Gilead is testing 7977 with Interferon and Ribavirin which tells me that they are looking for a quick way to make money out of 7977 while preventing a competitor from gaining any market share. I would have thought that they would have made huge profits out of 7977 even working with BMS. If that had been the case, we would genuinely be very close to decent cure right now. It would be only months away. With Gilead's present attitude, it will be years, who knows how many. One journalist postured that Gilead's behaviour has set the cure delivery date back 10-years.
I have taken both Interferon and Ribavirin together. That experience has made want to avoid both drugs, even with 7977.
I can't feel in the least bit warm and fuzzy towards Gilead. They just want to monopolize the HCV treatment market like they did with AIDs. Monopoly is a very bad thing for patients. If Gilead achieve's a monopoly the company will stop research and improvements as soon as they have something they can sell for a profit. There will be no incentive for them to do better. Expensive research will stop. Everybody will start to think that HCV is beaten even if we are having to take drugs with horrible side effects. Gilead will be able to name whatever price they like for the drugs. That is what they are really aiming for.
Sincere best wishes to you for achieving a cure though.
Gilead is testing 7977 with Interferon and Ribavirin which tells me that they are looking for a quick way to make money out of 7977 while preventing a competitor from gaining any market share. I would have thought that they would have made huge profits out of 7977 even working with BMS. If that had been the case, we would genuinely be very close to decent cure right now. It would be only months away. With Gilead's present attitude, it will be years, who knows how many. One journalist postured that Gilead's behaviour has set the cure delivery date back 10-years.
I have taken both Interferon and Ribavirin together. That experience has made want to avoid both drugs, even with 7977.
I can't feel in the least bit warm and fuzzy towards Gilead. They just want to monopolize the HCV treatment market like they did with AIDs. Monopoly is a very bad thing for patients. If Gilead achieve's a monopoly the company will stop research and improvements as soon as they have something they can sell for a profit. There will be no incentive for them to do better. Expensive research will stop. Everybody will start to think that HCV is beaten even if we are having to take drugs with horrible side effects. Gilead will be able to name whatever price they like for the drugs. That is what they are really aiming for.
Sincere best wishes to you for achieving a cure though.
No, Bristol Myers has said it will not work with Gilead.
http://www.marketwatch.com/story/gilead-bristol-myers-hep-c-regimen-promising-2012-04-19
Please sign the petition:
http://www.change.org/petitions/gilead-sciences-please-collaborate-with-bristol-myers-for-the-cure-for-hepatitis-c-now
http://www.marketwatch.com/story/gilead-bristol-myers-hep-c-regimen-promising-2012-04-19
Please sign the petition:
http://www.change.org/petitions/gilead-sciences-please-collaborate-with-bristol-myers-for-the-cure-for-hepatitis-c-now
If BMS really won't work with Gilead, then I stand corrected. I still don't retract what I said about Gilead wanting to monopolize the market and the final outcome of that though. No time today to follow this up but will definitely look at that petition page as soon as I can.
Oops, I got that backwards. Sorry Gilead refuses to work with Bristol Myers.
I got up and out of the house too early this morning. Looks like my dyslexia has kicked in !
I got up and out of the house too early this morning. Looks like my dyslexia has kicked in !
Wow. D71352 was just presenting information as Gilead's future plans. Why jump on D71352 with so little knowledge about GS-7977, how a pharmaceutical company runs their business?
Fmulder is was not a Gilead drug that had its trials stopped.
'Bristol-Myers Squibb has halted development of a potential hepatitis C drug after nine participants in a clinical trial of the therapy were hospitalized and one died.'
'Idenix Pharmaceuticals, based in Cambridge, Massachusetts, had a drug in trial that acted with a mechanism similar to that of BMS-986094. That trial has now been put on partial hold by the FDA as a result of the BMS trial failure'
OdinLovesLife
'GS-5885, is too new at phase 1.'
Actually GS-5885 is in Phase 2 now (Study 120) examining 12 weeks of treatment with GS-5885, GS-9451, tegobuvir (GS-9190) and ribavirin.
Please post your source for GS-5885 causing cancer.
Please post speculation regarding phrama companies in the Hepatitis Social Forum. We are try to present real data not opinions here so that people can learn about current and possible future treatments and people's experiences with these treatments.
D71352 thanks for presenting the info on the one pill. I'm sure some people are interest in this information.
Thanks for sharing!
Hector
Fmulder is was not a Gilead drug that had its trials stopped.
'Bristol-Myers Squibb has halted development of a potential hepatitis C drug after nine participants in a clinical trial of the therapy were hospitalized and one died.'
'Idenix Pharmaceuticals, based in Cambridge, Massachusetts, had a drug in trial that acted with a mechanism similar to that of BMS-986094. That trial has now been put on partial hold by the FDA as a result of the BMS trial failure'
OdinLovesLife
'GS-5885, is too new at phase 1.'
Actually GS-5885 is in Phase 2 now (Study 120) examining 12 weeks of treatment with GS-5885, GS-9451, tegobuvir (GS-9190) and ribavirin.
Please post your source for GS-5885 causing cancer.
Please post speculation regarding phrama companies in the Hepatitis Social Forum. We are try to present real data not opinions here so that people can learn about current and possible future treatments and people's experiences with these treatments.
D71352 thanks for presenting the info on the one pill. I'm sure some people are interest in this information.
Thanks for sharing!
Hector
First time I ever heard the word decent and pharm company mentioned in the same sentence. The Pharm companies make a lot of people cry, but not because they adore the company :-)
Sorry but all pharm's treat their "guinea pigs" great! You are helping to make them billions in the future.
Don't get me wrong I was a lab rat myself. I'm very grateful to Vertex for "curing" me of HCV.
Anyway it is great the pharms continue to find better treatments. I don't see any single dose hcv drugs hitting the market for many years to come.
best of luck
Sorry but all pharm's treat their "guinea pigs" great! You are helping to make them billions in the future.
Don't get me wrong I was a lab rat myself. I'm very grateful to Vertex for "curing" me of HCV.
Anyway it is great the pharms continue to find better treatments. I don't see any single dose hcv drugs hitting the market for many years to come.
best of luck
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I don't understand anyone saying it's put the cure back ten years! Gilead will be filing for FDA approval next year for 7977+riba for geno's 2 and 3 and look to hopefully follow that up in 2014 for geno 1's with 7977+5885.
What does one mean that they'll stop research? When you have the cure, you have the cure! Gilead have never stopped research with HIV. In fact they're the leading pharma in that department and I would say that the world should be very happy about that. Personally, I'm feeling very good about what they have to offer.