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135456 tn?1301437624

Can anyone recomend a liver friendly antidepressant I can take when I start treatment?

I have taken wellbutrin before on treatment and stopped when my  doctor and I found out it can cause major hepatoxicity.  Any one have good results on other ones( Effexor, Lexapro, etc..)?
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189269 tn?1189755825
I have been on Anafrinil for 1 year to treat ocd, it is a older ad mainly prescribed for ocd, hopefully when I start tx that will be all I need. My mind has been twisted from my ocd most of my life and the sx I think will be easy to deal with.
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372366 tn?1284403873
I am taking effexor for the peginterferon associated depression, started on 150/day a few weeks before treatment and went down to 75/day.It's been almost one year now, only side effect is brain shivers.And the treatment has worked so far.

Harry
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Avatar universal
No, don't take Fluoxetin AND Paroxetin, and don't take anything without doctor's order.
SAM-e does roughly the same as these meds, i.e. raises serotonin and dopamine levels, but by a different mechanism. The B-vitamins,including Choline & Inositol, are often depleted in HCV, especially during Peg-Riba treatment, and this can contribute to depression and lassitude. The carnitine and taurine have a related function, taurine  is often deficient because the liver isn't processing animal proteins too well.
They also all help SAM-e absorption and functioning.
Best.
Timo
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179856 tn?1333547362
I went on Paxill a month before treatment.  Never had any problems with it and also...I kept forgetting to refill it for about a week after I ran out.  I expected a major problem with withdrawl but...nothing happened that I noticed really.


Deb - Honestly the best news would have been a better number but as long as you get to a two log drop at week 12 you should be alright - of course you HAVE to be UND by week 24 and may have to consider extending treatment if you are positive between week 12 - 24 but...you're not done yet my friend!  A week 4 test is very important to have for a lot of reasons but is NOT the end of the world, although the number is very high you can now see that you are not reacting as nearly as much as you should.

did your doc discuss upping your riba by a pill or anything?  Are you taking them faithfully with breakfast and dinner making sure you are eating plenty of FAT with them?  This helps them bind to it and not just get flushed out. If you aren't doing it...make sure you start asap.

I've never heard anybody say they wished they could have MORE infergen before - you have a good sense of will and I wish you all the luck in the world.  Seriously though as many times as you've treated I don't understand why your doc isn't a bit more concerned about you having such a high viral load at week 4.  Any way you can get a second opinion from another doctor?

Another Deb :)
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Avatar universal
love your name, fighting the dragon Perfect name! ! So just to simplify and  you take Fluoetin & Paroxetin, to increase serotonin and a combination of b vitamins and these other drugs?  Or are these other drugs sul, ei  the vitamins? Sorry, I am little dense here!  
I also use ginger tea to settle stomach, and live on Ritz crackers!  I feel ok this time mentaly, but physically, this is harder.
I also make myself stretch every day, and find if I hit shower early, I feel better,  try and walk and loads of water!  The neuprogen causes bad big bone ache, so  struggle with that a bit, but hey at least I know it is making white blood cells!
I have only every taken anti depresesants, while on tx,  so not sure what all this are? So keeping both of your posts!
Thanks Grandma and St George and Timo!
Helpful - 0
Avatar universal
Have you tried SAM-e ? ADs like Fluoxetin & Paroxetin raise serotonin levels and reduce depression, but take several weeks before the effects are felt, while SAM-e acts rapidly to improve mood and is hepatoprotective. It also has long been used in Europe to control the pain of arthritis and fibromyalgia, often in preference to NSAIDs, and has virtually no negative effects or toxicity. But it is expensive and it should not be used in bipolar disorders.
I take 400mg together with B-1, B-2, B-6, B-12, Sulbutiamine, Choline & Inositol, Taurine and Acetyl-L-Carnitine and a mug of green tea with ginger and cinnamon as soon as I can struggle out of bed and in 20-25 minutes I can face the day with a smile.
Must be taken on an empty stomach and half an hour before eating anything else.

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