Awesome news.Thanks for all the info in the past.You'll come by now and then.The door I'm sure will always be open.Go make memories with your life, family.Congratulations on everything you've been through. T.
Wow, it sounds like the polymerase inhibitors are even better than the protease inhibitors. I kind of thought they would be the next big thing. I hope I don't ever have to personally find out! I'm hoping the protease inhibitor I just opted myself out of at week 28 will do the trick. I think the shorter treatments will do just fine, too. I think the longer treatments run the risk of permanent sides, and was willing to be the guinea pig for hitting it with the PI on the back end, instead of the front. 85% for 1s, Wow!
The polymerase inhibitor I was on, R7128, is now recruiting (or maybe already in) Phase II trials. From what I read they are going to be doing a few different dose levels and shortening the Peg and riba to 24 weeks in some arms. I don't have it in front of me but it was something like that. I personally feel the 24 week will work well. I cleared as do most by week 4. This drug has had a 85+% clearance rate in early trials for geno 1's which is tremendous. Shortening the treatment to 24 weeks will be nice as you don't have to endure the peg for too long.
I have not seem any SVR data yet but I am sure it will be out by te next AASLD meeting (Boston). The other thing I might mention is the drug itself has no side effects. All of the sides are from the peg and riba.
thanks for the well wishes.
Glad to hear you are doing so well and want to thank your for exchanging emails a while back. As you may recall, we share the same Dr. in Philly and both agreed he is one of the good guys in the field besides being an excellent doctor. I finished my 48 weeks on June 18th and so far am still UND, feeling much better, and anxious for my 12 week study visit next month. Thanks again for the update and the encouragement to the forum.
First off, great to hear your good news! Second...very interesting. I think you are the first person I've seen that is on a polymerase inhibitor. I just stopped early on a protease inhibitor study (I completed the 12 weeks of study drug after crossing over from the control arm with not so good results on SOC), and when I was contemplating my decision, I asked the doctor about retreating should I need to. He said never again on protease inhibitor, but polymerase inhibitor is different, so it could work. Phase I trial? I think I remember seeing something in Clinical Care's reports about the study you were on. Very interested in following your results and hoping they continue to be good ones!
COngruatulations, and wishing you more of the same!
jd
Congratulations on your great news!
It's wonderful to see you clear after seeing your name and reading your posts for so long.
Your story is inspiring.
Stay well,
Mike
Congrats and thanks for posting post-tx details.
Great to hear your wonderful results. Thanks for posting and letting us know your progress.
Congratulations! Great news!
Feel well.
Charm27
Nice post DS, and wonderful to hear of your results, your recoup and your holiday!!! I'm so glad the hard work paid dividends; congrats - it's sounding really really good for you!!
Great to hear the good news from you, Dragonslayer! You are almost home free
congratulations on your new free dom best wishes
congratulations and good for you on your 3 mos post testing!