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Fast Food Likely to Accelerate Hepatitis C

Man, I' glad I did not read this while treating. Now this is something to chew on.


March 07, 2008 Printer-friendly version  

Fast Food Likely to Accelerate Hepatitis C
According to new research from Sweden, grabbing a quick burger and fries is just as harmful to the liver as drinking alcohol. Since liver damage carries a graver risk to those living with Hepatitis C, eating low-fat meals is more important to this population than ever.

by Nicole Cutler, L.Ac.

New research from Sweden confirms that eating fast food can cause substantial liver damage. Luckily, the liver is one of our few organs capable of regenerating new, healthy cells. Thus, the injury inflicted from occasionally ordering dinner from a drive-through window can be reversed with a focused effort. Unfortunately, those battling Hepatitis C have a diminished ability to regenerate new liver cells and therefore have a harder time reversing liver damage. This means that the liver cell death incurred from eating the high-fat meals typical of fast food restaurants may be more detrimental to those already living with a chronic liver disease such as Hepatitis C.

The Hepatitis C virus (HCV) is one of the most common causes of chronic liver disease in the United States. Accounting for about 15 percent of acute viral hepatitis, 60 to 70 percent of chronic hepatitis and up to 50 percent of cirrhosis, end-stage liver disease and liver cancer, experts estimate that 4.1 million Americans are currently infected with HCV. While many more people live with HCV than die from it, the distinguishing factor between the two is learning how to prevent incurring further liver damage.

The HCV Disadvantage
The progression of liver disease is marked by a greater proportion of liver cell death than the creation of new, healthy liver cells. Due to a buildup of localized scar tissue, the following cascade of events demonstrates why those with HCV are prone to a worsening of their condition:

1. The Hepatitis C virus infects and kills liver cells.

2. In response to liver cell death, the body initiates an immune response, which causes inflammation.

3. In an attempt to limit the spread of infection, the immune system lays down collagen fibers between liver cells. These fibers are the building blocks of scar tissue.

4. Normally, as an infection or injury resolves, the collagen matrix enclosing the injury is dissolved and allows the tissue to return to normal. However, this web of collagen in people with chronic HCV grows more rapidly than it can dissolve.

5. As more collagen accumulates, the resulting scar tissue restricts living liver cells from access to nutrients and oxygen-rich blood.

6. The restricted access to blood causes even more quarantined liver cells to die. As such, HCV progressively scars the liver.

Since people living with HCV have this consistent battle being waged in their liver, they are more vulnerable to toxins that could damage this organ.

The Danger of Fast Food
Many things we breathe, ingest, swallow or otherwise absorb into our bodies pose a threat to the liver. A universally acknowledged cause of chronic liver disease, drinking alcohol is one of the most obvious ways to poison a liver. While most people might not categorize their lunch as toxic, millions of Americans are damaging their liver by eating fast food. A small Swedish study published in the February 2008 edition of the journal Gut found that even a brief fast-food binge combined with too little exercise can induce liver damage.

In this study, 18 slim, healthy participants stuck to a fast food diet, mostly consuming of hamburger meals from popular chains twice a day for four weeks while refraining from exercise. At the end of the experiment, participants not only gained an average of 16 pounds, but blood tests also showed evidence that those eating fast food incurred liver damage.

In the Swedish study, those gorging on fast food meals showed a dramatic increase in alanine aminotransferases (ALT) levels over a very short period of time. An enzyme produced in liver cells, ALT leaks into the bloodstream as liver cells are damaged. A result of liver cell damage, ALT elevations can be caused by any liver disease, hepatic inflammation or toxin.

Previous research has shown that a diet high in fat and calories, the hallmark of greasy, fast food, puts people at greater risk for obesity and type 2 diabetes, cardiovascular disease and heart failure. However, this Swedish study shows that doubling caloric intake without adding exercise also puts hepatic health in jeopardy. When excessive calories and fat overloads the liver’s ability to filter the blood, fat builds up in the liver cells and leads to liver damage. Considering that a majority of the study participants developed pathological ALT levels within just one week after eating fast food, this negative impact can occur relatively quickly.

Most people with HCV are aware that drinking alcohol causes liver cell death and can accelerate the severity of their liver disease. However, now their physicians must relay that alcohol is not the only thing they must navigate away from. Since eating a large quantity of high-fat foods (even for a short time period) while refraining from physical activity can damage the liver, people with HCV must avoid this combination. Since harboring the Hepatitis C virus makes recovery from liver damage a great challenge, hepatologists across the globe will be putting greater emphasis on sticking to a healthy, low-fat diet and adhering to an active lifestyle.

42 Responses
Avatar universal
Happy you posted this although the evidence highlighted by the study has been around for some time now.

Yes, heavy drinking is not good for the liver, but sometimes I get the feeling that people translate being a non-drinker with a liver healthy lifestyle, while I'm sure more than a few wash their Big Mac and Fries down with their non-alcoholic drink. Eating a diet high in saturated fats, having a high BMI, smoking and not exercising enough are all insults to the liver.

Tonight I'm having wild Salmon, vegetables, some whole wheat Scandanavian crackers and a glass or two of Malbec. The Malbec btw is on the recommendation of my heaptologist who feels it will help my lipid profile. Does anyone think a dinner of steak and fries and a non-alcoholic drink is better for the liver?

BTW pre treatment, I was able to normalize my liver enzymes by adhering to a very low fat diet, the Pritkin diet to be exact. Right now, I'm trying to adhere to a higher (good) fat but lower carb diet -- something in the neighborhood of the South Beach or Zone diet.  I'm not a dietician but I think both approaches probably work in their own way. What you don't want is a diet high in saturated fats and carbs. The worst of all worlds and also called the typical American Diet.

Excuse the rant but I'd die for a Big Mac right now instead of the Salmon so I'm using this study as motivation :)

-- Jim
Avatar universal
Got off the soap box before I had a chance to mention excess sugars such as table sugar, honey, soda drinks, most deserts and even fruit when in excess.
Avatar universal
315996 tn?1429057829
I just had 2 cheeseburgers and a root beer float.

Avatar universal
No dessert?....no deep fried chocolate bars?....

i guess you dont like alfafa sprouts?
Avatar universal
OK, I'll concede the fast food but rootbeer too!?!  Can't I please have the odd rootbeer - I only make floats for special occasions (or comfort)  Where does it end?
314554 tn?1337457719
I don't know many grown ups who it fast/junk food ~
(especially If pizza is not included in that category)

Unfortunately, junk food is often an unavoidable reality with grandchildren -
and there is no denying the smell of those crispy brown fries is mouth watering.
Avatar universal
I'm not a junk food junkie, but my down fall is sugar. Sure do love those rootbeer floats, mmm, mmm.
Avatar universal
Far as i go as for junkfood is those power bars...and soya ice cream...i do like yogurt too...all organic of course....and the odd veggie pizza
476246 tn?1418874514
None of it for me.... no soft drinks, sugar etc... and I hate ice cream. I dunno what happened, as I used to love it. Well, a veggie pizza or a durum falafel maybe a few times a year.
Avatar universal
I'll have to admit that I was a junk food junkie in the beginning of treatment and through most of it. The sudden weight loss and depression sent me into a tail spin. I had worked throughout treatment and most of my time was spent on the road in between jobs and had easy excess fast food. I would pack a lunch which most of the time was gone by mid morning and the need to fill the empty spot led me to the burger joints and even then it did not stay with me very long either way and it became a vicious circle. I had it stuck in my head about the riba absorption factor riba and did not consider and thing else and after reading this article I feel very confident about my SVR status even though I now have to reverse what I did during treatment.

Avatar universal
I also ate lots of fats during treatment, not only because of riba absorption but because I was only able to eat a very select group of let's call them "comfort" foods. Healthy foods like fish and vegetables made me nauceous even to think about. So I tried to eat healthy before and after treatment but during treatment I ate to survive, meaning I ate whatever I could get down to temper the signficicant weight loss I was having. Ironically, my blood lipids were never better as on this diet and no doubt because the interferon messed big time with my metabolism. Not that I had a choice, but given my cholesterol was around 140 during treatment plus the BMI of almost an anorexic LOL I doubt very much the temporary high fat diet did any harm.

-- Jim
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