(see my previous post to Jim)
Back in October, what kind of blood test did they do? What was your fasting blood sugar? Did they check your insulin level? How about a 2 hour glucose tolerance test?
You see....when you become insulin resistant (insensitive to insulin), the pancreas works harder and produces more insulin....and sometimes it makes too much and that causes your blood sugar to go down too low.....like maybe 40.
Co
You are on record as saying that the chances for RVR are close to zero for someone who is IR going into treatment. BB is super RVR so either you're wrong about that, or he was not IR going into treatment or had it under control. Which is it and I won't even charge you $23.
I found a post written by BklynBoy81 back in October that says....
"Mom is a diabetic so i get to check my sugar levels once in awhile.. The one reason i found out that i was Hep C Pos was because my sugar would drop to 40.. 40 is kind of scary so i thought i was a diabetic or hyperglycemic and so i got some blood work done"
Now....what were you saying about him not being insulin resistant?
Co
I'm home and catching my breath. Hate stairs.
Vertex says NO to only one particular class of blood pressure medication called CALCIUM CHANNEL BLOCKERS. Everything Vertex lists belongs to this class.
So in a nutshell, don't take any calcium channel blockers during treatment, according to Vertex. Simple.
I'm willing to accept that at face value, since I'm not a fan of that class due to tachycardia as a side effect.
The other broad classes are:
1) diuretics
2) betablockers
3) ACE inhibitors
4) ARB's
I have to say diuretics are often the first line of tx in the U.S., so the fact the trial didn't prescribe it but a betablocker instead is interesting. I'm still puzzled if there's a rationale for prescribing a betablocker for BB during tx, given that it's not commonly prescribed anymore.
Co, if ACE's are so much in the cardiology eye, why wasn't he prescribed one? Yes, I love everything I read about it but here I am resistant to it during tx. Sorry to be a pain but I'm perplexed and frustrated at taking the creme de la creme and getting lousy results.
TTYL
"Has anyone told you that you see life through IR colored glasses LOL"
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ROFL....never that nicely.
"I do think it's an important topic but "
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It's THE most important host factor in the prediction of response. I would say it's important.
"especially if someone RVRd."
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"Exquisitively sensitive to interferon". Exquisitively sensitive to insulin is what I think they are....LOL You'll see....one day I'll be proven right.
"Someone posted a few weeks ago that their doctor already has one patient who needed a transplant, the damage caused by one of the IR drugs."
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I'm going to have to set a limit to how many times I argue the same topic with you. And I'll start charging you $23 every time you go above the limit....LOL
Avandia can cause liver failure. There are 14 reported cases....but NONE with Metformin.
Co
There's a list at the bottom of the page of some commonly used....
http://en.wikipedia.org/wiki/ACE_inhibitor
Co