Can u b RIBA resistant?

[candyce1953]

I am geno 1B/ I am TT
I have heard that makes me possibly interfereon resistant

But does that also make me ribivarin resistant
Or is there another test for that?
Thank you C

[candyce1953]

Thanks will give it a try!

[jules2551]

I made it through the first paragragh and that was all she wrote!  LOL  way over my head(s)

[1oftheclub222]

I found an article regarding this...to be honest I tried to read it and understand it, but it made my head spin half way through...in case anyone is interested in reading it and can comprehend what it is saying, maybe you can summerize for me?

http://jvi.asm.org/content/79/4/2346.full

[candyce1953]

Thank you Will and Slideman
Yes Will I think you did give me info about Intfereon
And Inc
But Inc and Vic are 63% success for TT I believe, and so I think I want to wait for non interfereon combo

That said it seems to me the early result of those trials seem to fair better with ribivarin included with the new orals
That said I wondered if there is a test for ribivarin resistance

I would hope I didn't have that type also
And can be treated with a higher success rate with all oral plus RIBA

[willbb]

I have never heard of a test that measures sensitivity to Riba.  There are tests available that can measure concentration in the blood .however it is not done while treating (altho hresp is in a study that measured it). Having the TT allele as you know makes you somewhat less sensitive to Inf. ,however as slideman points out with one of the Daa's it is less of a concern..not totally irrelevant just less...
.Canydyce I believe I copied to you some months ago the ad-hoc analysis of treating with Inci as it pertains to having the TT allele..possibly I am mistaken.

best...
Will

[slideman]

I too am TT. 1A geno, but I have been und since wk 4, and was also und at 12 wks post. The PI's dont seem to care about TT, and I have never heard of TT having any affect on riba.

[candyce1953]

Thanks Pooh

[pooh55811]

I do not know the answer to your question but I will bump you up so that other more knowledgeable people will hopefully respond.

[candyce1953]

Ok tx

[jules2551]

Sorry didn't mean to hijack the thread.  Not tx yet within next month hopefully.  I will send you PM

[candyce1953]

No didn't start yet, am afraid if int in tx
Have been seeing rheumi for RA
Am thinking of non int CT maybe instead

I forgot did u start tx yet?

[jules2551]

Candyce,
     Did you start tx yet?  I looked at your profile and couldn't tell.  Sorry I have brain damage and not on tx yet LOL

Have a great day!
Jules