If you are not suffering with anemia then stick to the max dose-tests consistently show higher riba,higher SVR.
He did not elaborate on the point other than to say that as my hgb was stable for the first two weeks and then collapsed during the subsequent two that it had taken four weeks for the riba to build up and that there was a good chance we could maintain the level with low dosing as it stayed so long in the system.
Inconclusive I know,but you can never really get into fine detail during a 20-30 min consultation.
I was wondering about your comment "My doctor (top man in the Hep C world) says that the riba build up in my system is so prolific that the low dose could be perfectly efficacious".
How did he come to that conclusion? Did he explain in any more detail? I've been sort of wondering about this myself lately. I seem to be pretty sensitive to riba, at 1200mg I feel like I'm going to crawl right out of my skin. I almost can't take it (and I'm not overly anemic either). Recently, I cut back to 600mg for a few days and started feeling SO much better, MUCH less itching and flaking. Now I'm up to 800mg and will eventually go to 1000mg, and maybe later back to 1200mg if I dare. I've been wondering if each person has a certain "personal threshold" for riba which actually may still be "perfectly efficacious" at doses under the normally considered optimum weight based dose (up to 1200mg). Of course I have no proof of that, but I do know that my body strongly reacts with pretty extreme discomfort at 1200mg of riba (which is what my weight warrants). I wonder if that discomfort level indicates that I'm over my personal toxicity tolerance, and if that might also translate into an indication of being equally toxic to the virus?
Last biopsy was 2003 and was 3 of 6 on the Ishak.
Doc won't biopsy me again.Fibroscan says 10.5.
I am probably borderline cirrhotic,well compensated at present.
I sincerely hope you can see your way through this to a much better outcome...what was your last biopsy grade? if you don't mind me asking?