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Avatar universal

Status of teleprevir and boceprevir

Just wondering if anyone has any updated status on teleprevir and boceprevir treatment for the average Joe.  My GI is telling me next year (2011).  I'm pretty far advanced in the disease and would like, well "like" is probably the wrong word, let's say I'm compelled to start treatment as soon as possible.  Is anyone besides trial patients getting teleprevir?  My platelets are under 100k so I don't meet trial protocol.  I wonder from time-to-time if teleprevir is available through other channels (black market perhaps).
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Avatar universal
"i do not recognize the virus itself as the big hazard we fear if the predicted damage is not occurring."

You have an active, chronic infection that is putting your immune system in high gear continuously.

I'd consider this a big hazard. At the very least, it has to be sapping energy.
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Avatar universal
Lots of talk about these high tech, high cost drugs. i don't hear anyone saying anything about high dosage Alpha Lipoic Acid used alternately with massive vitamin rich nutrient IV therapy. i have been doing this stuff for about 7 months now. It is a very low risk process with small side effects. While my viral load has risen and fallen my liver function has been outstanding. Enzme levels are very low and i find that very promising.
i do not recognize the virus itself as the big hazard we fear if the predicted damage is not occurring. Monetary cost of this course of treatment is $100.00 to $150.00 per treatment (materials only). My insurance will not pay for said materials but they do pay 80% of each visit to the naturpath. To learn more check out Dr Mark Berkson of Las Cruzes New Mexico. Pretty easy to find on a google search.
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154668 tn?1290115995
Vertex to Ask for Telaprevir OK Later in 2010
http://abcnews.go.com
Vertex Pharmaceuticals to seek regulatory OK for telaprevir hepatitis drug in 2nd half of 2010

Biotechnology company Vertex Pharmaceuticals Inc. said Monday it plans to seek regulatory approval of the experimental hepatitis C drug telaprevir as scheduled during the second half of 2009.

Telaprevir is one of several potential hepatitis C treatments in development. If approved, it could face competition from Schering-Plough Corp.'s experimental hepatitis C drug boceprevir.

Meanwhile, the company will tell investors at a conference it expects a loss of less than $650 million in fiscal 2009, versus a loss of $459.9 million in fiscal 2008, or $397.5 million on an adjusted basis.

Vertex has about $1.3 billion in cash, cash equivalents and marketable securities.

The company will report 2009 financial results and provide a 2010 outlook on Feb. 4.

Shares of Vertex rose $1.28, or 3.2 percent, to $41.95 in midday trading.





Boceprevir is a little tolerant on the platelet threshold.
Helpful - 0
179856 tn?1333547362
Hang in there guys at least these drugs do look like they will make it out - that is something that we've seen not happen many many times over the years.  But not this time I hope (although there is still no guarantee).

Have you ever treated before? Which geno are you? Many people these days are having luck with plain old SOC treatment.  With information that we have now (Ie: how important the 4 week test is, extending tx if necessary, the importance of fat and ribavirin to get  the serum level up of WEIGHT based riba, adding Alinia things like that) many people are now getting to SVR who never had a chance before.

I understand the desire to start right away.  What stage are you? I wanted to treat regardless which stage I was but when I found out I was stage 3 realized I had no choice and went for it. It worked even though it wasn't easy.

Why, if you are advanced, would he make you wait another year (although a year in heptime if you take good care of that liver is not really that long since it's usually so slowly progressing).

Good luck.
Helpful - 0
897070 tn?1320652629
I completely understand your frustrations and fear Bill this question is driving me crazy.Cirrhotic and waiting for people to get this drug out is driving me nuts.
Helpful - 0
1117750 tn?1307386569
mid 2011 in states ............if you got the money why not try dont ask where though i have no idea...
Helpful - 0
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