I can think of a dozen studies I'd like to see, like female hormone levels on TX and loads of post-TX studies, but I think it will be a really long time before any scientist or funder cares about those things. All research roads seem to point to shorter TX and non-interferon TX. Those are good goals but doesn't clarify all the goofy problems that pop up after the major goal, SVR, has been reached.
On a quick lunch
First Mike, it may have been apparent what I meant;
mj6000 wrote post TX and you wrote post SVR----that is what I *mean* to write.
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No time to elaborate on your query but I agree with what you wrote and I think that I more or less said that. I meant to dismiss the possibility, not allow it was a possibility.
There are numbers of people who an SVR does not prove durable and there are theories as to why. I don't think good data exists as to why it is though.
I don't know if I can write this clearly enough while in a hurry.... but..... at what point to you think it's safe to drink? After TX if UND?
OR after SVR?
IF your answer is after SVR but NOT post TX then would that be due to the grey area where alcohol might impact the durability of the potential SVR?
If I follow your logic (about deactivation theory) it would seem that it suggests that one could drink alcohol as soon as one was UND. My response, as unclear as it may have been was intending to write about that period between post TX and SVR. I still didn't think that there was much evidence to suggest "reactivation".
I don't know the answer; I don't know if modern medicine knows yet and it is almost bound to be differing answers for different situations.
Yes, though, I agree; I've not seen any evidence studies or what not of alcohol "reactivating" .......causing to become HCV positive again any SVR'ed patients.
Sorry; this is thrown together quickly. Gotta go.
I hope that I clarified what I meant; not muddied it further.
Willy
I started to drink again a couple of weeks post tx after consulting with my dr. I'm a geno 1b, guessing stage 0 since I started tx 6 months after acute stage, and were still und 9 weeks post. My dr said alcohol had no influence on the matter of relapsing or not as soon I had finished the treatment.
I am holding up in front of myself the thought of being able to celebrate with a drink when I am done with this treatment.
It helps me to have something to look forward to. Kind of like a reward for being so good (since last March)
In a way, I hope I don't like drinking, when I do try it again.
I do feel that since I have been so good, and that I was able to quit on the spot, the day I received the news of abnormal liver function (high alt/ast readings), that I deserve a treat.
I quit just like that, without any complaint, and I am damn proud of myself (I was a daily after-work cocktail hour drinker, since I was 16! (I'm 48 now) and psychologically, I miss it terribly.
Although right now on tx, I am definitely feeling too tired all the time to really even want to drink.)
I won't be done with the tx until March, and then that will be a full year without a drop of alcohol. So, if I continue to be UND (und at 4 weeks), and if my ALT/AST continue the direction they are going now, and soon get to be within the normal range, I WILL have my cocktail, maybe not a vodka/tonic (my drink of choice), but instead a glass of really good red wine. Yea baby! I can't wait.
If you dont wait for your 6 month SVR...you are taking risks....what happens if you relapse at the 6 month PCR test?....this means you would have been drinkn on a infected liver bteween the end of your tx and the 6 month mark and more damage will be done...if it was me....id wait for the 6 month,which i am BTW
It is something to think about, definitely, but I also need something to look forward to. March is already so far away to me. I just really need something to look forward to.