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179856 tn?1333547362

RG7128 80% Und at 12 Weeks

Pharmasset shares rise on positive study results

Shares Pharmasset Inc. rose Wednesday after the company said the hepatitis C drug candidate key goals in a midstage study.

THE SPARK: Pharmasset RG7128 met safety and tolerability goals in the Phase 2b clinical trial, which involved 408 patients. The interim data also showed that 80 percent of patients had undetectable levels of the virus after receiving a 12-week regimen, compared with 50 percent taking the current standard of care.

THE BIG PICTURE: Pharmasset is a clinical-stage company, with no products on the market. RG7128 is the most advance product candidate it has in the partnership with Roche.

THE ANALYSIS: "We believe the safety, efficacy and resistance profiles revealed today are very encouraging, and that RG7128 is now a further, de-risked program," said Wedbush analyst Y. Katherine Xu, while reaffirming an "Outperform" rating with a $44 price target.

SHARE ACTION: Up rose $1.22, or 4.2 percent, to $30.50 in afternoon trading. The stock has traded between $10.15 and $33.50 over the last 52 weeks.
Best Answer
29837 tn?1414534648
It's a shame a lot of us can't wait, as this is just the tip of the iceberg as far as upcoming Hep C drugs. I love it when they all get off the starting line and try to reach the end of the race before other pharmaceutical companies do.

This can only be a positive incentive for more and more pharmaceutical companies to come up with a less and less brutal treatment plan... I’m sure all the pharmaceutical companies know that the winner will be the one with a treatment with NO side effects...

Mag
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Avatar universal
I think r7128 is the most promising drug currently in phase 2 studies.  I hope that they can now move on to phase 3 and get it out here to us sooooonest!

dointime    
Helpful - 0
179856 tn?1333547362
This can only be a positive incentive for more and more pharmaceutical companies to come up with a less and less brutal treatment plan"

I agree just as much as people like to complain about big pharma they are the future for heppers (and other diseases too) and without them and their profit incentives - nothing would ever get developed would it?
Helpful - 0
979080 tn?1323433639
RG7128 in my view will be the next best PI , because of its saftey profile and bacuse
it is cross geno. ( it did show some kidney problems in resus monkeys)

It is a triple  tx , RG7128 +SOC.

What counts here are SVR rates , not hot air on the stock market.


b
Helpful - 0
Avatar universal
Wow, this is just amazing. Was it monotherapy with RG7128 or in combination with SOC? Thank you very much for posting.
Helpful - 0
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